lisuride-6682 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the lisuride-6682 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
ADAM22 ADAM metallopeptidase domain 22
ADGRG1 adhesion G protein-coupled receptor G1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BAGE B melanoma antigen
BAIAP3 BAI1-associated protein 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP8A bone morphogenetic protein 8a
C11ORF1 chromosome 11 open reading frame 1
CALCR calcitonin receptor
CCDC134 coiled-coil domain containing 134
CCR7 chemokine (C-C motif) receptor 7
CD160 CD160 molecule
CES3 carboxylesterase 3
CFAP70 cilia and flagella associated protein 70
CFLAR CASP8 and FADD-like apoptosis regulator
CHAT choline O-acetyltransferase
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPT1A carnitine palmitoyltransferase 1A (liver)
CRYGD crystallin, gamma D
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DIAPH2-AS1 DIAPH2 antisense RNA 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK10 dedicator of cytokinesis 10
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPS8L1 EPS8-like 1
FLT3LG fms-related tyrosine kinase 3 ligand
FRMPD1 FERM and PDZ domain containing 1
GJA8 gap junction protein, alpha 8, 50kDa
HEXA hexosaminidase A (alpha polypeptide)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOOK1 hook microtubule-tethering protein 1
HOXB6 homeobox B6
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ITGA9 integrin, alpha 9
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT2A K(lysine) acetyltransferase 2A
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KMT2A lysine (K)-specific methyltransferase 2A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LINC00115 long intergenic non-protein coding RNA 115
LINC00341 long intergenic non-protein coding RNA 341
MAPK8 mitogen-activated protein kinase 8
MBTD1 mbt domain containing 1
MTCP1 mature T-cell proliferation 1
NFX1 nuclear transcription factor, X-box binding 1
NOX1 NADPH oxidase 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAPPA2 pappalysin 2
PDE4B phosphodiesterase 4B, cAMP-specific
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTN pleiotrophin
PTRF polymerase I and transcript release factor
QSER1 glutamine and serine rich 1
RAB6B RAB6B, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARG retinoic acid receptor, gamma
RASA3 RAS p21 protein activator 3
RBMXL2 RNA binding motif protein, X-linked-like 2
RPL10 ribosomal protein L10
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SIRT4 sirtuin 4
SLC6A16 solute carrier family 6, member 16
SNX13 sorting nexin 13
SSX3 synovial sarcoma, X breakpoint 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TADA3 transcriptional adaptor 3
TCP11L1 t-complex 11, testis-specific-like 1
TFCP2L1 transcription factor CP2-like 1
TFDP3 transcription factor Dp family, member 3
TJP3 tight junction protein 3
TLK1 tousled-like kinase 1
TLR5 toll-like receptor 5
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSPAN2 tetraspanin 2
WDR59 WD repeat domain 59
ZNF334 zinc finger protein 334
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALOX12 arachidonate 12-lipoxygenase
ANXA2P1 annexin A2 pseudogene 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCDC186 coiled-coil domain containing 186
CCL27 chemokine (C-C motif) ligand 27
CDK20 cyclin-dependent kinase 20
CFAP69 cilia and flagella associated protein 69
CHRDL1 chordin-like 1
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CST1 cystatin SN
CYB5R2 cytochrome b5 reductase 2
CYSLTR1 cysteinyl leukotriene receptor 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
EFNB1 ephrin-B1
ETNK2 ethanolamine kinase 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM86C1 family with sequence similarity 86, member C1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FOXN2 forkhead box N2
FURIN furin (paired basic amino acid cleaving enzyme)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
HDAC11 histone deacetylase 11
HESX1 HESX homeobox 1
HIST1H3I histone cluster 1, H3i
HMGB3P1 high mobility group box 3 pseudogene 1
HOXA1 homeobox A1
HOXA7 homeobox A7
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT54 intraflagellar transport 54
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL22 interleukin 22
ITGB7 integrin, beta 7
ITPKA inositol-trisphosphate 3-kinase A
KIFC3 kinesin family member C3
KLHL4 kelch-like family member 4
KRT86 keratin 86, type II
LY6D lymphocyte antigen 6 complex, locus D
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYRM9 LYR motif containing 9
MGP matrix Gla protein
MRPL46 mitochondrial ribosomal protein L46
MTSS1L metastasis suppressor 1-like
MUC2 mucin 2, oligomeric mucus/gel-forming
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NNAT neuronatin
NOD1 nucleotide-binding oligomerization domain containing 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NTF3 neurotrophin 3
ODF2 outer dense fiber of sperm tails 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR6 progestin and adipoQ receptor family member VI
PC pyruvate carboxylase
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRSS53 protease, serine, 53
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB40A RAB40A, member RAS oncogene family
SAYSD1 SAYSVFN motif domain containing 1
SIRT6 sirtuin 6
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNRPN small nuclear ribonucleoprotein polypeptide N
ST7L suppression of tumorigenicity 7 like
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
STMN3 stathmin-like 3
SYT17 synaptotagmin XVII
TAGLN transgelin
THBS3 thrombospondin 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TM6SF1 transmembrane 6 superfamily member 1
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TMPRSS2 transmembrane protease, serine 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSKU tsukushi, small leucine rich proteoglycan
TTLL7 tubulin tyrosine ligase-like family member 7
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VN1R1 vomeronasal 1 receptor 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB33 zinc finger and BTB domain containing 33
ZNF358 zinc finger protein 358
ZNF385D zinc finger protein 385D
ZNF747 zinc finger protein 747