lmo2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description LIM domain only 2 (rhombotin-like 1)|LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008] (NCBI Entrez Gene Database, 4005)
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Genes

29 genes co-occuring with the biological term lmo2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BEX2 brain expressed X-linked 2
C1ORF27 chromosome 1 open reading frame 27
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELSPBP1 epididymal sperm binding protein 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
GATA2 GATA binding protein 2
GCSAM germinal center-associated, signaling and motility
HLF hepatic leukemia factor
IRF4 interferon regulatory factor 4
JAK2 Janus kinase 2
KDM3B lysine (K)-specific demethylase 3B
KLF1 Kruppel-like factor 1 (erythroid)
LDB1 LIM domain binding 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MIR125B1 microRNA 125b-1
MIR142 microRNA 142
MIR223 microRNA 223
MYB v-myb avian myeloblastosis viral oncogene homolog
NRP2 neuropilin 2
PRDM1 PR domain containing 1, with ZNF domain
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
STIL SCL/TAL1 interrupting locus
TAL1 T-cell acute lymphocytic leukemia 1
TCF3 transcription factor 3
TLX1 T-cell leukemia homeobox 1
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
ZEB1 zinc finger E-box binding homeobox 1