| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the lobeline-2763 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AIM2 | absent in melanoma 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| ANGPTL2 | angiopoietin-like 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARSD | arylsulfatase D |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF6B | activating transcription factor 6 beta |
| ATXN2L | ataxin 2-like |
| BGN | biglycan |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3AR1 | complement component 3a receptor 1 |
| CD1A | CD1a molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD83 | CD83 molecule |
| CEP112 | centrosomal protein 112kDa |
| CNTN1 | contactin 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTSF | cathepsin F |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DRD1 | dopamine receptor D1 |
| DRD5 | dopamine receptor D5 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ETV5 | ets variant 5 |
| FAM214B | family with sequence similarity 214, member B |
| FST | follistatin |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HFE | hemochromatosis |
| HOXB6 | homeobox B6 |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| IDS | iduronate 2-sulfatase |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IL6ST | interleukin 6 signal transducer |
| IRF8 | interferon regulatory factor 8 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KIAA0319L | KIAA0319-like |
| KRT19P2 | keratin 19 pseudogene 2 |
| LENEP | lens epithelial protein |
| LIMCH1 | LIM and calponin homology domains 1 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LRRC6 | leucine rich repeat containing 6 |
| MAGEB2 | melanoma antigen family B2 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MINK1 | misshapen-like kinase 1 |
| MYOZ1 | myozenin 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP88 | nucleoporin 88kDa |
| OSBPL10 | oxysterol binding protein-like 10 |
| OTOR | otoraplin |
| PHOX2B | paired-like homeobox 2b |
| PKP1 | plakophilin 1 |
| PLP1 | proteolipid protein 1 |
| POU2F2 | POU class 2 homeobox 2 |
| RIN3 | Ras and Rab interactor 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTN2 | reticulon 2 |
| S100A9 | S100 calcium binding protein A9 |
| SAMD4B | sterile alpha motif domain containing 4B |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPPL2B | signal peptide peptidase like 2B |
| STMN1 | stathmin 1 |
| STX7 | syntaxin 7 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAGLN3 | transgelin 3 |
| THRB | thyroid hormone receptor, beta |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| TRIM31 | tripartite motif containing 31 |
| UPK3B | uroplakin 3B |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| WSCD1 | WSC domain containing 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADM | adrenomedullin |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL7C | B-cell CLL/lymphoma 7C |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CD2AP | CD2-associated protein |
| CD302 | CD302 molecule |
| CHKB | choline kinase beta |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CSTA | cystatin A (stefin A) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTSV | cathepsin V |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DNA2 | DNA replication helicase/nuclease 2 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHA2 | EPH receptor A2 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM189B | family with sequence similarity 189, member B |
| FAM50B | family with sequence similarity 50, member B |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FHOD1 | formin homology 2 domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| FZD4 | frizzled class receptor 4 |
| GAA | glucosidase, alpha; acid |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HIRA | histone cell cycle regulator |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST3H2A | histone cluster 3, H2a |
| HOXC13 | homeobox C13 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA1551 | KIAA1551 |
| KIF16B | kinesin family member 16B |
| KRBOX4 | KRAB box domain containing 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MTMR11 | myotubularin related protein 11 |
| MTMR6 | myotubularin related protein 6 |
| MXD3 | MAX dimerization protein 3 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NME7 | NME/NM23 family member 7 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PKN1 | protein kinase N1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRAF2 | PRA1 domain family, member 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIX1 | SIX homeobox 1 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SNIP1 | Smad nuclear interacting protein 1 |
| STXBP2 | syntaxin binding protein 2 |
| THYN1 | thymocyte nuclear protein 1 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM104 | transmembrane protein 104 |
| TMEM110 | transmembrane protein 110 |
| TMEM180 | transmembrane protein 180 |
| TMEM254 | transmembrane protein 254 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TSPO | translocator protein (18kDa) |
| UBXN8 | UBX domain protein 8 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WASF1 | WAS protein family, member 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF468 | zinc finger protein 468 |
