lobeline-5784 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the lobeline-5784 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACSS3 acyl-CoA synthetase short-chain family member 3
ADCK4 aarF domain containing kinase 4
ADORA1 adenosine A1 receptor
ANXA10 annexin A10
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C1ORF95 chromosome 1 open reading frame 95
C7ORF69 chromosome 7 open reading frame 69
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN17 claudin 17
CROCC ciliary rootlet coiled-coil, rootletin
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCT dopachrome tautomerase
DIAPH2-AS1 DIAPH2 antisense RNA 1
DOCK5 dedicator of cytokinesis 5
EDA ectodysplasin A
EFCAB6 EF-hand calcium binding domain 6
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFR3B EFR3 homolog B (S. cerevisiae)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FCAR Fc fragment of IgA receptor
FGF5 fibroblast growth factor 5
FPR1 formyl peptide receptor 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIF gastric intrinsic factor (vitamin B synthesis)
GK glycerol kinase
HOMER3 homer scaffolding protein 3
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
INSL4 insulin-like 4 (placenta)
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD17 potassium channel tetramerization domain containing 17
KDM4B lysine (K)-specific demethylase 4B
KSR1 kinase suppressor of ras 1
LINC00312 long intergenic non-protein coding RNA 312
LPPR4 lipid phosphate phosphatase-related protein type 4
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LUZP4 leucine zipper protein 4
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MFAP3 microfibrillar-associated protein 3
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCAPH2 non-SMC condensin II complex, subunit H2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRCAM neuronal cell adhesion molecule
OSGIN2 oxidative stress induced growth inhibitor family member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PDE10A phosphodiesterase 10A
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4D phosphodiesterase 4D, cAMP-specific
PLA2G10 phospholipase A2, group X
PLD1 phospholipase D1, phosphatidylcholine-specific
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PNLIPRP2 pancreatic lipase-related protein 2
PVR poliovirus receptor
RAB6A RAB6A, member RAS oncogene family
RANBP1 RAN binding protein 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RIF1 replication timing regulatory factor 1
RPL35A ribosomal protein L35a
SAYSD1 SAYSVFN motif domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLMO1 slowmo homolog 1 (Drosophila)
SMAD6 SMAD family member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STK24 serine/threonine kinase 24
STON1 stonin 1
TAGLN3 transgelin 3
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TGFBR1 transforming growth factor, beta receptor 1
TMPRSS3 transmembrane protease, serine 3
TPSAB1 tryptase alpha/beta 1
TRIM48 tripartite motif containing 48
TRIO trio Rho guanine nucleotide exchange factor
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTLL5 tubulin tyrosine ligase-like family member 5
UBE2B ubiquitin-conjugating enzyme E2B
VAMP5 vesicle-associated membrane protein 5
VWA5A von Willebrand factor A domain containing 5A
ZBED2 zinc finger, BED-type containing 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF254 zinc finger protein 254
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ART1 ADP-ribosyltransferase 1
BAG4 BCL2-associated athanogene 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL9 B-cell CLL/lymphoma 9
BEX4 brain expressed, X-linked 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF45 chromosome 5 open reading frame 45
CA11 carbonic anhydrase XI
CCNJL cyclin J-like
CCNO cyclin O
CD53 CD53 molecule
CES3 carboxylesterase 3
CHMP6 charged multivesicular body protein 6
CREB5 cAMP responsive element binding protein 5
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDN dendrin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DNAH7 dynein, axonemal, heavy chain 7
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EXOC6B exocyst complex component 6B
FAM110B family with sequence similarity 110, member B
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FAT4 FAT atypical cadherin 4
GDAP1 ganglioside induced differentiation associated protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPR19 G protein-coupled receptor 19
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
HIST1H1D histone cluster 1, H1d
HIST1H1T histone cluster 1, H1t
HIST1H2BJ histone cluster 1, H2bj
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IFT81 intraflagellar transport 81
IMPG2 interphotoreceptor matrix proteoglycan 2
KRT8P12 keratin 8 pseudogene 12
KRT9 keratin 9, type I
LAX1 lymphocyte transmembrane adaptor 1
LMBR1L limb development membrane protein 1-like
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MATN3 matrilin 3
MICALL2 MICAL-like 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MT1F metallothionein 1F
MTERF4 mitochondrial transcription termination factor 4
MXRA8 matrix-remodelling associated 8
NABP1 nucleic acid binding protein 1
NID2 nidogen 2 (osteonidogen)
OVGP1 oviductal glycoprotein 1, 120kDa
PDE12 phosphodiesterase 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PODXL2 podocalyxin-like 2
PRR3 proline rich 3
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPRH protein tyrosine phosphatase, receptor type, H
PXMP4 peroxisomal membrane protein 4, 24kDa
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RETN resistin
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SDAD1 SDA1 domain containing 1
SNTG1 syntrophin, gamma 1
SP1 Sp1 transcription factor
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A3 steroid 5 alpha-reductase 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3 stromal antigen 3
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TBX19 T-box 19
TMEM212 transmembrane protein 212
TNNI3 troponin I type 3 (cardiac)
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
ZNF10 zinc finger protein 10
ZNF124 zinc finger protein 124
ZNF141 zinc finger protein 141
ZNF197 zinc finger protein 197
ZNF358 zinc finger protein 358
ZNF423 zinc finger protein 423
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768