| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the lomefloxacin-4281 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AIRE | autoimmune regulator |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C3AR1 | complement component 3a receptor 1 |
| CADM4 | cell adhesion molecule 4 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CASZ1 | castor zinc finger 1 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD48 | CD48 molecule |
| CD6 | CD6 molecule |
| CLTB | clathrin, light chain B |
| CPNE7 | copine VII |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DKFZP434C153 | DKFZP434C153 protein |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DST | dystonin |
| DUSP7 | dual specificity phosphatase 7 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ENO3 | enolase 3 (beta, muscle) |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GIPR | gastric inhibitory polypeptide receptor |
| GK | glycerol kinase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPC3 | glypican 3 |
| GPX7 | glutathione peroxidase 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HHIPL2 | HHIP-like 2 |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KSR1 | kinase suppressor of ras 1 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LOC57399 | uncharacterized gastric protein ZA52P |
| LOXL3 | lysyl oxidase-like 3 |
| LSP1 | lymphocyte-specific protein 1 |
| LTC4S | leukotriene C4 synthase |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MSX2 | msh homeobox 2 |
| MUC8 | mucin 8 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NPTX1 | neuronal pentraxin I |
| NRP2 | neuropilin 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| ONECUT2 | one cut homeobox 2 |
| OTUD7B | OTU deubiquitinase 7B |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PHOX2A | paired-like homeobox 2a |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKP3 | plakophilin 3 |
| PLXND1 | plexin D1 |
| PON3 | paraoxonase 3 |
| PROL1 | proline rich, lacrimal 1 |
| RARG | retinoic acid receptor, gamma |
| REC8 | REC8 meiotic recombination protein |
| RETN | resistin |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SORT1 | sortilin 1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPN | sialophorin |
| SSTR5 | somatostatin receptor 5 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAC3 | tachykinin 3 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TNXB | tenascin XB |
| TPP1 | tripeptidyl peptidase I |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| WIZ | widely interspaced zinc finger motifs |
| WT1 | Wilms tumor 1 |
| WTAP | Wilms tumor 1 associated protein |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF609 | zinc finger protein 609 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BTC | betacellulin |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CCDC94 | coiled-coil domain containing 94 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CEP295 | centrosomal protein 295kDa |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CORO1A | coronin, actin binding protein, 1A |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| EHF | ets homologous factor |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPPK1 | epiplakin 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM186A | family with sequence similarity 186, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPX2 | glutathione peroxidase 2 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3F | histone cluster 1, H3f |
| HIST1H4C | histone cluster 1, H4c |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KLC2 | kinesin light chain 2 |
| KLHL28 | kelch-like family member 28 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAGEA6 | melanoma antigen family A6 |
| MED18 | mediator complex subunit 18 |
| METTL16 | methyltransferase like 16 |
| MMP3 | matrix metallopeptidase 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYL5 | myosin, light chain 5, regulatory |
| NABP1 | nucleic acid binding protein 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| PCDHA9 | protocadherin alpha 9 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| RAB11B | RAB11B, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBM42 | RNA binding motif protein 42 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RFX7 | regulatory factor X, 7 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| S100A3 | S100 calcium binding protein A3 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCG5 | secretogranin V |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCRN3 | secernin 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP4 | Sp4 transcription factor |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TEP1 | telomerase-associated protein 1 |
| TIPRL | TOR signaling pathway regulator |
| TMEM209 | transmembrane protein 209 |
| TSPAN2 | tetraspanin 2 |
| USP36 | ubiquitin specific peptidase 36 |
| VGF | VGF nerve growth factor inducible |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| YY2 | YY2 transcription factor |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF264 | zinc finger protein 264 |
| ZNF286A | zinc finger protein 286A |
| ZNF426 | zinc finger protein 426 |
| ZNF573 | zinc finger protein 573 |
| ZNF652 | zinc finger protein 652 |
| ZNF667 | zinc finger protein 667 |
| ZNF701 | zinc finger protein 701 |
| ZNF74 | zinc finger protein 74 |
