| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the lomefloxacin-4745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADCK4 | aarF domain containing kinase 4 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| B9D1 | B9 protein domain 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| CCDC28B | coiled-coil domain containing 28B |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDK6 | cyclin-dependent kinase 6 |
| CEP135 | centrosomal protein 135kDa |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COL10A1 | collagen, type X, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRAT | carnitine O-acetyltransferase |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYBB | cytochrome b-245, beta polypeptide |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMPK | dystrophia myotonica-protein kinase |
| DOCK6 | dedicator of cytokinesis 6 |
| DUOX2 | dual oxidase 2 |
| E2F2 | E2F transcription factor 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FRMD8 | FERM domain containing 8 |
| GAB1 | GRB2-associated binding protein 1 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR21 | G protein-coupled receptor 21 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSTM5 | glutathione S-transferase mu 5 |
| HDAC7 | histone deacetylase 7 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXA9 | homeobox A9 |
| IL33R | interleukin 33 receptor |
| ING2 | inhibitor of growth family, member 2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIAA0087 | KIAA0087 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KRT14 | keratin 14, type I |
| LAMB4 | laminin, beta 4 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIMD1 | LIM domains containing 1 |
| LMNA | lamin A/C |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MED25 | mediator complex subunit 25 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MOB3B | MOB kinase activator 3B |
| MPZ | myelin protein zero |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTMR8 | myotubularin related protein 8 |
| MTSS1 | metastasis suppressor 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRL | neural retina leucine zipper |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OCA2 | oculocutaneous albinism II |
| OPRM1 | opioid receptor, mu 1 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PKN2 | protein kinase N2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRY | PTPN13-like, Y-linked |
| RAB6A | RAB6A, member RAS oncogene family |
| RAP1GAP | RAP1 GTPase activating protein |
| RELN | reelin |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A4 | S100 calcium binding protein A4 |
| SERHL2 | serine hydrolase-like 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SNX29 | sorting nexin 29 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRCAP | Snf2-related CREBBP activator protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYT5 | synaptotagmin V |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TCF12 | transcription factor 12 |
| TFEB | transcription factor EB |
| TNMD | tenomodulin |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| VGLL3 | vestigial-like family member 3 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XDH | xanthine dehydrogenase |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AMT | aminomethyltransferase |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CLDN1 | claudin 1 |
| CLIC2 | chloride intracellular channel 2 |
| CLSTN2 | calsyntenin 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DFNB31 | deafness, autosomal recessive 31 |
| DMTN | dematin actin binding protein |
| DNAL4 | dynein, axonemal, light chain 4 |
| EDAR | ectodysplasin A receptor |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM46C | family with sequence similarity 46, member C |
| FKRP | fukutin related protein |
| GAMT | guanidinoacetate N-methyltransferase |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GID4 | GID complex subunit 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFI35 | interferon-induced protein 35 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIF13A | kinesin family member 13A |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MEFV | Mediterranean fever |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMRN2 | multimerin 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MSI1 | musashi RNA-binding protein 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEK11 | NIMA-related kinase 11 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PCDHA6 | protocadherin alpha 6 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PER3 | period circadian clock 3 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| QSER1 | glutamine and serine rich 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAI2 | retinoic acid induced 2 |
| REEP4 | receptor accessory protein 4 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFPL3 | ret finger protein-like 3 |
| RHBDD3 | rhomboid domain containing 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCG2 | secretogranin II |
| SDC3 | syndecan 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIRT6 | sirtuin 6 |
| SKI | SKI proto-oncogene |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STIM1 | stromal interaction molecule 1 |
| STK16 | serine/threonine kinase 16 |
| STON1 | stonin 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBX19 | T-box 19 |
| TESK1 | testis-specific kinase 1 |
| TIGD6 | tigger transposable element derived 6 |
| TLR5 | toll-like receptor 5 |
| TMEM38B | transmembrane protein 38B |
| TMEM53 | transmembrane protein 53 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRIM36 | tripartite motif containing 36 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VEGFB | vascular endothelial growth factor B |
| VIM | vimentin |
| ZNF227 | zinc finger protein 227 |
| ZNF248 | zinc finger protein 248 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF442 | zinc finger protein 442 |
| ZNF551 | zinc finger protein 551 |
| ZNF787 | zinc finger protein 787 |
