| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the lomustine-7045 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA1 | annexin A1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATRN | attractin |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C12ORF4 | chromosome 12 open reading frame 4 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBR3 | carbonyl reductase 3 |
| CCNE1 | cyclin E1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDYL | chromodomain protein, Y-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CREM | cAMP responsive element modulator |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELMO2 | engulfment and cell motility 2 |
| EPHA2 | EPH receptor A2 |
| ESRRA | estrogen-related receptor alpha |
| ETV5 | ets variant 5 |
| FAM188A | family with sequence similarity 188, member A |
| FOSL1 | FOS-like antigen 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRB10 | growth factor receptor-bound protein 10 |
| HBEGF | heparin-binding EGF-like growth factor |
| HMOX1 | heme oxygenase 1 |
| HOMER3 | homer scaffolding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICOSLG | inducible T-cell co-stimulator ligand |
| ING1 | inhibitor of growth family, member 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGB5 | integrin, beta 5 |
| KIAA0319L | KIAA0319-like |
| KIF5C | kinesin family member 5C |
| LDB1 | LIM domain binding 1 |
| LOC644450 | uncharacterized LOC644450 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MIR22HG | MIR22 host gene |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCGF3 | polycomb group ring finger 3 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCLO | piccolo presynaptic cytomatrix protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLL | polymerase (DNA directed), lambda |
| PRMT2IP | PRMT2 interacting protein |
| PRNP | prion protein |
| PSEN1 | presenilin 1 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| SAPCD1 | suppressor APC domain containing 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| STIP1 | stress-induced phosphoprotein 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TES | testin LIM domain protein |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM16 | tripartite motif containing 16 |
| TXNRD1 | thioredoxin reductase 1 |
| UNKL | unkempt family zinc finger-like |
| VEGFA | vascular endothelial growth factor A |
| ZNF609 | zinc finger protein 609 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACTN3 | actinin, alpha 3 (gene/pseudogene) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| CSTA | cystatin A (stefin A) |
| CTSF | cathepsin F |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EMID1 | EMI domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM46C | family with sequence similarity 46, member C |
| FAM63A | family with sequence similarity 63, member A |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FUZ | fuzzy planar cell polarity protein |
| GATA4 | GATA binding protein 4 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLB1L | galactosidase, beta 1-like |
| GLCE | glucuronic acid epimerase |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| H2AFJ | H2A histone family, member J |
| HIST1H2BI | histone cluster 1, H2bi |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXB2 | homeobox B2 |
| HOXC6 | homeobox C6 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| JAK2 | Janus kinase 2 |
| KLK5 | kallikrein-related peptidase 5 |
| LHX6 | LIM homeobox 6 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MXD3 | MAX dimerization protein 3 |
| MYLIP | myosin regulatory light chain interacting protein |
| N4BP3 | NEDD4 binding protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRSN2 | neurensin 2 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OSMR | oncostatin M receptor |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLSCR4 | phospholipid scramblase 4 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMP22 | peripheral myelin protein 22 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| RAB27B | RAB27B, member RAS oncogene family |
| RGS17 | regulator of G-protein signaling 17 |
| RGS2 | regulator of G-protein signaling 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF2 | ring finger protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SALL2 | spalt-like transcription factor 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMAD7 | SMAD family member 7 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TESK2 | testis-specific kinase 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMC5 | transmembrane channel-like 5 |
| TMEM104 | transmembrane protein 104 |
| TRAF5 | TNF receptor-associated factor 5 |
| TXNIP | thioredoxin interacting protein |
| UBQLN4 | ubiquilin 4 |
| VASH2 | vasohibin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF350 | zinc finger protein 350 |
