| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the loperamide-1533 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACTL8 | actin-like 8 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATF3 | activating transcription factor 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDON | cell adhesion associated, oncogene regulated |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC11A | C-type lectin domain family 11, member A |
| CLIP3 | CAP-GLY domain containing linker protein 3 |
| COL1A1 | collagen, type I, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DOCK5 | dedicator of cytokinesis 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| FBXO21 | F-box protein 21 |
| FOXG1 | forkhead box G1 |
| GK | glycerol kinase |
| GOLGA6A | golgin A6 family, member A |
| GPATCH4 | G patch domain containing 4 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR137 | G protein-coupled receptor 137 |
| GSN | gelsolin |
| HFE | hemochromatosis |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOMER3 | homer scaffolding protein 3 |
| HOXB6 | homeobox B6 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL21R | interleukin 21 receptor |
| IL36RN | interleukin 36 receptor antagonist |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JAK3 | Janus kinase 3 |
| LDLR | low density lipoprotein receptor |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPIN1 | lipin 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MDFI | MyoD family inhibitor |
| MEGF6 | multiple EGF-like-domains 6 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPZ | myelin protein zero |
| MTCP1 | mature T-cell proliferation 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| MZF1 | myeloid zinc finger 1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PADI1 | peptidyl arginine deiminase, type I |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PER1 | period circadian clock 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| RAB27B | RAB27B, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPON2 | spondin 2, extracellular matrix protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYNJ2 | synaptojanin 2 |
| TGFB2 | transforming growth factor, beta 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TP63 | tumor protein p63 |
| TRIM2 | tripartite motif containing 2 |
| TSPAN9 | tetraspanin 9 |
| TUBA3C | tubulin, alpha 3c |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZFP37 | ZFP37 zinc finger protein |
| ZMYM6 | zinc finger, MYM-type 6 |
| ZNF606 | zinc finger protein 606 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARRB1 | arrestin, beta 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL2L2 | BCL2-like 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPN5 | calpain 5 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLSTN2 | calsyntenin 2 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CORO7 | coronin 7 |
| CTSF | cathepsin F |
| CTSV | cathepsin V |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| EHD3 | EH-domain containing 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBRS | fibrosin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GLCE | glucuronic acid epimerase |
| GMPR | guanosine monophosphate reductase |
| GRPR | gastrin-releasing peptide receptor |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN1 | mucolipin 1 |
| METTL2B | methyltransferase like 2B |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP9 | matrix metallopeptidase 9 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MVP | major vault protein |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OLFML3 | olfactomedin-like 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNA3 | plexin A3 |
| PODXL2 | podocalyxin-like 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PROCR | protein C receptor, endothelial |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD51AP1 | RAD51 associated protein 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF123 | ring finger protein 123 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SERINC5 | serine incorporator 5 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPAG1 | sperm associated antigen 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STRA6 | stimulated by retinoic acid 6 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYCP2 | synaptonemal complex protein 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TESC | tescalcin |
| TMEM180 | transmembrane protein 180 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| WDR60 | WD repeat domain 60 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF180 | zinc finger protein 180 |
| ZNF480 | zinc finger protein 480 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
