| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the loperamide-1949 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACVR2B | activin A receptor, type IIB |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AGRP | agouti related neuropeptide |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 |
| ARSJ | arylsulfatase family, member J |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| ATXN2 | ataxin 2 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| CA12 | carbonic anhydrase XII |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CCPG1 | cell cycle progression 1 |
| CD53 | CD53 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLTA | clathrin, light chain A |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COPS7B | COP9 signalosome subunit 7B |
| CPD | carboxypeptidase D |
| CRCP | CGRP receptor component |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CTH | cystathionine gamma-lyase |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTNA | dystrobrevin, alpha |
| DXO | decapping exoribonuclease |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GAS7 | growth arrest-specific 7 |
| GPN3 | GPN-loop GTPase 3 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYG2 | glycogenin 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HMOX2 | heme oxygenase 2 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| INSIG1 | insulin induced gene 1 |
| KDM6B | lysine (K)-specific demethylase 6B |
| LDLR | low density lipoprotein receptor |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| MAP7D3 | MAP7 domain containing 3 |
| MECP2 | methyl CpG binding protein 2 |
| MED14 | mediator complex subunit 14 |
| MLH3 | mutL homolog 3 |
| MSH3 | mutS homolog 3 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCKAP1 | NCK-associated protein 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NKX3-1 | NK3 homeobox 1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PASK | PAS domain containing serine/threonine kinase |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLIN2 | perilipin 2 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRSS8 | protease, serine, 8 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RHAG | Rh-associated glycoprotein |
| RPL7 | ribosomal protein L7 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SFTPB | surfactant protein B |
| SIRT3 | sirtuin 3 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STX16 | syntaxin 16 |
| STX5 | syntaxin 5 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TMEM8B | transmembrane protein 8B |
| TMEM97 | transmembrane protein 97 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRD | T cell receptor delta locus |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UPK1B | uroplakin 1B |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WWOX | WW domain containing oxidoreductase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF165 | zinc finger protein 165 |
| ZNF609 | zinc finger protein 609 |
| ZNF611 | zinc finger protein 611 |
| Symbol | Name |
|---|---|
| ANXA2P3 | annexin A2 pseudogene 3 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFNB2 | ephrin-B2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC2 | excision repair cross-complementation group 2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EVPL | envoplakin |
| EXOSC9 | exosome component 9 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM222B | family with sequence similarity 222, member B |
| FAM50B | family with sequence similarity 50, member B |
| FDXR | ferredoxin reductase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GPATCH1 | G patch domain containing 1 |
| GPKOW | G patch domain and KOW motifs |
| GSTT1 | glutathione S-transferase theta 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HELLS | helicase, lymphoid-specific |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| HMG20A | high mobility group 20A |
| ICAM3 | intercellular adhesion molecule 3 |
| JUNB | jun B proto-oncogene |
| KIAA1549L | KIAA1549-like |
| KIFC1 | kinesin family member C1 |
| KLHL21 | kelch-like family member 21 |
| KRBOX4 | KRAB box domain containing 4 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LIPT1 | lipoyltransferase 1 |
| LMTK1 | lemur tail kinase 1 |
| LRRC20 | leucine rich repeat containing 20 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MGA | MGA, MAX dimerization protein |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MPG | N-methylpurine-DNA glycosylase |
| MPST | mercaptopyruvate sulfurtransferase |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MSRB1 | methionine sulfoxide reductase B1 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCTP | phosphatidylcholine transfer protein |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMM2 | phosphomannomutase 2 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PYGB | phosphorylase, glycogen; brain |
| RNMTL1 | RNA methyltransferase like 1 |
| RPL34 | ribosomal protein L34 |
| RUVBL2 | RuvB-like AAA ATPase 2 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SOD3 | superoxide dismutase 3, extracellular |
| STK25 | serine/threonine kinase 25 |
| TGS1 | trimethylguanosine synthase 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM187 | transmembrane protein 187 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TSPYL1 | TSPY-like 1 |
| TTI1 | TELO2 interacting protein 1 |
| UBAC1 | UBA domain containing 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| URGCP | upregulator of cell proliferation |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| WDR13 | WD repeat domain 13 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF532 | zinc finger protein 532 |
| ZNF552 | zinc finger protein 552 |
