| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the loperamide-2033 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADORA1 | adenosine A1 receptor |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ARSB | arylsulfatase B |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCL7A | B-cell CLL/lymphoma 7A |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCNG2 | cyclin G2 |
| CD82 | CD82 molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CETN1 | centrin, EF-hand protein, 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLIC5 | chloride intracellular channel 5 |
| CMC4 | C-x(9)-C motif containing 4 |
| COG5 | component of oligomeric golgi complex 5 |
| CRY2 | cryptochrome circadian clock 2 |
| CTSE | cathepsin E |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAO | D-amino-acid oxidase |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EHD1 | EH-domain containing 1 |
| ELMO2 | engulfment and cell motility 2 |
| EPHB2 | EPH receptor B2 |
| ETV5 | ets variant 5 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FZD4 | frizzled class receptor 4 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GDF11 | growth differentiation factor 11 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GON4L | gon-4-like (C. elegans) |
| HFE | hemochromatosis |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ICAM2 | intercellular adhesion molecule 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLHL18 | kelch-like family member 18 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTB4R | leukotriene B4 receptor |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MEF2D | myocyte enhancer factor 2D |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MVK | mevalonate kinase |
| MYT1 | myelin transcription factor 1 |
| NFYA | nuclear transcription factor Y, alpha |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIDD1 | p53-induced death domain protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLS1 | plastin 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RASL11B | RAS-like, family 11, member B |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN3 | Ras and Rab interactor 3 |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SECISBP2L | SECIS binding protein 2-like |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRR | serine racemase |
| TBL1X | transducin (beta)-like 1X-linked |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMF1 | TATA element modulatory factor 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WDR48 | WD repeat domain 48 |
| YLPM1 | YLP motif containing 1 |
| ZNF444 | zinc finger protein 444 |
| ZNF500 | zinc finger protein 500 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APOBR | apolipoprotein B receptor |
| ARMC7 | armadillo repeat containing 7 |
| AVEN | apoptosis, caspase activation inhibitor |
| BCL7C | B-cell CLL/lymphoma 7C |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CAB39 | calcium binding protein 39 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CCDC6 | coiled-coil domain containing 6 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLDND1 | claudin domain containing 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPOX | coproporphyrinogen oxidase |
| CRTAP | cartilage associated protein |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CYCS | cytochrome c, somatic |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DIXDC1 | DIX domain containing 1 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DYM | dymeclin |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM192A | family with sequence similarity 192, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GAB2 | GRB2-associated binding protein 2 |
| GIMAP6 | GTPase, IMAP family member 6 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HDAC4 | histone deacetylase 4 |
| IL4R | interleukin 4 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIFAP3 | kinesin-associated protein 3 |
| KIFC1 | kinesin family member C1 |
| LXN | latexin |
| MAEA | macrophage erythroblast attacher |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MED4 | mediator complex subunit 4 |
| MELK | maternal embryonic leucine zipper kinase |
| METTL18 | methyltransferase like 18 |
| METTL8 | methyltransferase like 8 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MTRF1 | mitochondrial translational release factor 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDCD10 | programmed cell death 10 |
| PDHX | pyruvate dehydrogenase complex, component X |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| REPIN1 | replication initiator 1 |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RINT1 | RAD50 interactor 1 |
| RNF141 | ring finger protein 141 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SATB1 | SATB homeobox 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SKI | SKI proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STK39 | serine threonine kinase 39 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCERG1 | transcription elongation regulator 1 |
| TEX30 | testis expressed 30 |
| TFB2M | transcription factor B2, mitochondrial |
| TIPIN | TIMELESS interacting protein |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TULP4 | tubby like protein 4 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USB1 | U6 snRNA biogenesis 1 |
| WDR18 | WD repeat domain 18 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF273 | zinc finger protein 273 |
