| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the loperamide-4672 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APOE | apolipoprotein E |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATG10 | autophagy related 10 |
| BBC3 | BCL2 binding component 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACYBP | calcyclin binding protein |
| CASC1 | cancer susceptibility candidate 1 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLTA | clathrin, light chain A |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CNTN5 | contactin 5 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DENND3 | DENN/MADD domain containing 3 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC7 | exocyst complex component 7 |
| FAM63B | family with sequence similarity 63, member B |
| FBXO22 | F-box protein 22 |
| FUS | FUS RNA binding protein |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GIMAP6 | GTPase, IMAP family member 6 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GP5 | glycoprotein V (platelet) |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HMOX1 | heme oxygenase 1 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IFT27 | intraflagellar transport 27 |
| IL1R1 | interleukin 1 receptor, type I |
| IL2 | interleukin 2 |
| INSIG1 | insulin induced gene 1 |
| ITGB4 | integrin, beta 4 |
| ITGB8 | integrin, beta 8 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0040 | KIAA0040 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL24 | kelch-like family member 24 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LDLR | low density lipoprotein receptor |
| LIPG | lipase, endothelial |
| LPIN1 | lipin 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MGAM | maltase-glucoamylase |
| MT1M | metallothionein 1M |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYO7A | myosin VIIA |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PPIAL4A | peptidylprolyl isomerase A (cyclophilin A)-like 4A |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RECQL5 | RecQ protein-like 5 |
| RGS4 | regulator of G-protein signaling 4 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD4 | SMAD family member 4 |
| SQSTM1 | sequestosome 1 |
| STC2 | stanniocalcin 2 |
| STX7 | syntaxin 7 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| THPO | thrombopoietin |
| TLK1 | tousled-like kinase 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOM1 | target of myb1 (chicken) |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF391 | zinc finger protein 391 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AEN | apoptosis enhancing nuclease |
| ANOS1 | anosmin 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BEND5 | BEN domain containing 5 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDN | dendrin |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EAF2 | ELL associated factor 2 |
| EN2 | engrailed homeobox 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPX2 | glutathione peroxidase 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAS2 | hyaluronan synthase 2 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3A | histone cluster 1, H3a |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IL20RA | interleukin 20 receptor, alpha |
| IL7R | interleukin 7 receptor |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIFC1 | kinesin family member C1 |
| KLHL25 | kelch-like family member 25 |
| KRT34 | keratin 34, type I |
| LOC730101 | uncharacterized LOC730101 |
| LRRC6 | leucine rich repeat containing 6 |
| LTC4S | leukotriene C4 synthase |
| MDFI | MyoD family inhibitor |
| METTL1 | methyltransferase like 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYOZ3 | myozenin 3 |
| NDP | Norrie disease (pseudoglioma) |
| NLK | nemo-like kinase |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRR15L | proline rich 15-like |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAB2 | stabilin 2 |
| STAC | SH3 and cysteine rich domain |
| STRN | striatin, calmodulin binding protein |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM121 | transmembrane protein 121 |
| TMSB15A | thymosin beta 15a |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| WDR3 | WD repeat domain 3 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF222 | zinc finger protein 222 |
| ZNF239 | zinc finger protein 239 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZNF770 | zinc finger protein 770 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
