| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the loperamide-5267 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CD300A | CD300a molecule |
| CD96 | CD96 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL13A1 | collagen, type XIII, alpha 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DMXL2 | Dmx-like 2 |
| DSG3 | desmoglein 3 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| FAM214B | family with sequence similarity 214, member B |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H3B | histone cluster 1, H3b |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HS1BP3 | HCLS1 binding protein 3 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| JUN | jun proto-oncogene |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LDLR | low density lipoprotein receptor |
| LEFTY1 | left-right determination factor 1 |
| LIF | leukemia inhibitory factor |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MT1F | metallothionein 1F |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLA2G3 | phospholipase A2, group III |
| POLM | polymerase (DNA directed), mu |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKCE | protein kinase C, epsilon |
| PTAFR | platelet-activating factor receptor |
| PYY | peptide YY |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RUNX1 | runt-related transcription factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SPEF1 | sperm flagellar 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TBX3 | T-box 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| VEGFA | vascular endothelial growth factor A |
| ZNF419 | zinc finger protein 419 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCNE1 | cyclin E1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXXC4 | CXXC finger protein 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| FAM204A | family with sequence similarity 204, member A |
| FBXO4 | F-box protein 4 |
| FGF23 | fibroblast growth factor 23 |
| FKBP5 | FK506 binding protein 5 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAS2 | growth arrest-specific 2 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GK3P | glycerol kinase 3 pseudogene |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPR27 | G protein-coupled receptor 27 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT54 | intraflagellar transport 54 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KITLG | KIT ligand |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEFV | Mediterranean fever |
| METTL16 | methyltransferase like 16 |
| MMP3 | matrix metallopeptidase 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MYOZ3 | myozenin 3 |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NLRX1 | NLR family member X1 |
| NOL12 | nucleolar protein 12 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| PARPBP | PARP1 binding protein |
| PCDHA5 | protocadherin alpha 5 |
| PITX1 | paired-like homeodomain 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFPL3 | ret finger protein-like 3 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| STIM1 | stromal interaction molecule 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCTN2 | tectonic family member 2 |
| THAP7 | THAP domain containing 7 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM212 | transmembrane protein 212 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TWISTNB | TWIST neighbor |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USB1 | U6 snRNA biogenesis 1 |
| VAX2 | ventral anterior homeobox 2 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF35 | zinc finger protein 35 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
