| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the loperamide-5632 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATF3 | activating transcription factor 3 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA9 | carbonic anhydrase IX |
| CCDC64 | coiled-coil domain containing 64 |
| CCNG2 | cyclin G2 |
| CD86 | CD86 molecule |
| CELF3 | CUGBP, Elav-like family member 3 |
| CFHR2 | complement factor H-related 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CUL7 | cullin 7 |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FBLN1 | fibulin 1 |
| FGF13 | fibroblast growth factor 13 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRY | furry homolog (Drosophila) |
| GRB10 | growth factor receptor-bound protein 10 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HCG4B | HLA complex group 4B (non-protein coding) |
| HFE | hemochromatosis |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT27 | intraflagellar transport 27 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KIAA1109 | KIAA1109 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LY9 | lymphocyte antigen 9 |
| LYZL6 | lysozyme-like 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK8 | mitogen-activated protein kinase 8 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MVK | mevalonate kinase |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OCLM | oculomedin |
| PAPPA2 | pappalysin 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH1 | protocadherin 1 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM14 | PR domain containing 14 |
| RAB40C | RAB40C, member RAS oncogene family |
| RND1 | Rho family GTPase 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERHL2 | serine hydrolase-like 2 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SQLE | squalene epoxidase |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TLR2 | toll-like receptor 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TULP1 | tubby like protein 1 |
| UBOX5 | U-box domain containing 5 |
| UBQLN4 | ubiquilin 4 |
| WDR62 | WD repeat domain 62 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ALPK1 | alpha-kinase 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNE1 | cyclin E1 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP45 | cilia and flagella associated protein 45 |
| CFD | complement factor D (adipsin) |
| CHKB | choline kinase beta |
| CTAGE9 | CTAGE family, member 9 |
| DEAF1 | DEAF1 transcription factor |
| DENND5B | DENN/MADD domain containing 5B |
| DNM1 | dynamin 1 |
| DRD1 | dopamine receptor D1 |
| DUSP2 | dual specificity phosphatase 2 |
| EPN1 | epsin 1 |
| ETNK2 | ethanolamine kinase 2 |
| ETV6 | ets variant 6 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRK | fyn-related Src family tyrosine kinase |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GMPR | guanosine monophosphate reductase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRAMD1C | GRAM domain containing 1C |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HPN | hepsin |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80D | INO80 complex subunit D |
| JMJD4 | jumonji domain containing 4 |
| KIAA0319L | KIAA0319-like |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRC61 | leucine rich repeat containing 61 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEFV | Mediterranean fever |
| NCALD | neurocalcin delta |
| NFS1 | NFS1 cysteine desulfurase |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OCA2 | oculocutaneous albinism II |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRAF2 | PRA1 domain family, member 2 |
| PRSS53 | protease, serine, 53 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SDC3 | syndecan 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMIM14 | small integral membrane protein 14 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIDR | scaffolding protein involved in DNA repair |
| SSBP3 | single stranded DNA binding protein 3 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TFF2 | trefoil factor 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMC7 | transmembrane channel-like 7 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VGF | VGF nerve growth factor inducible |
| WDR3 | WD repeat domain 3 |
| WDR33 | WD repeat domain 33 |
| WDR46 | WD repeat domain 46 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF711 | zinc finger protein 711 |
| ZNF750 | zinc finger protein 750 |
| ZW10 | zw10 kinetochore protein |
