| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the lovastatin-2494 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABLIM1 | actin binding LIM protein 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANGPTL2 | angiopoietin-like 2 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARMC7 | armadillo repeat containing 7 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BARX1 | BARX homeobox 1 |
| CCDC64 | coiled-coil domain containing 64 |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIC5 | chloride intracellular channel 5 |
| CLTB | clathrin, light chain B |
| COL1A1 | collagen, type I, alpha 1 |
| CREM | cAMP responsive element modulator |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DNPEP | aspartyl aminopeptidase |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| FGFR2 | fibroblast growth factor receptor 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GNLY | granulysin |
| GNMT | glycine N-methyltransferase |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GPR162 | G protein-coupled receptor 162 |
| GPR22 | G protein-coupled receptor 22 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HSPA12A | heat shock 70kDa protein 12A |
| IDS | iduronate 2-sulfatase |
| IFNA14 | interferon, alpha 14 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGLJ3 | immunoglobulin lambda joining 3 |
| ING2 | inhibitor of growth family, member 2 |
| IRF4 | interferon regulatory factor 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0125 | KIAA0125 |
| KIAA0754 | KIAA0754 |
| KIF3A | kinesin family member 3A |
| KSR1 | kinase suppressor of ras 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMA2 | laminin, alpha 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRRC1 | leucine rich repeat containing 1 |
| LRRC6 | leucine rich repeat containing 6 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MYBPH | myosin binding protein H |
| NAG18 | NAG18 mRNA |
| NEFM | neurofilament, medium polypeptide |
| NF1 | neurofibromin 1 |
| NMT2 | N-myristoyltransferase 2 |
| NRG1 | neuregulin 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCH1 | phospholipase C, eta 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTCH2 | patched 2 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RORC | RAR-related orphan receptor C |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SH3PXD2A | SH3 and PX domains 2A |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPATA1 | spermatogenesis associated 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TEF | thyrotrophic embryonic factor |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TNC | tenascin C |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACVR2B | activin A receptor, type IIB |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AHR | aryl hydrocarbon receptor |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| APH1B | APH1B gamma secretase subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| ART1 | ADP-ribosyltransferase 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASZ1 | castor zinc finger 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CXXC4 | CXXC finger protein 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DOK3 | docking protein 3 |
| EFNA3 | ephrin-A3 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| G0S2 | G0/G1 switch 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA5 | homeobox A5 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0753 | KIAA0753 |
| KPTN | kaptin (actin binding protein) |
| LATS1 | large tumor suppressor kinase 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEB2 | melanoma antigen family B2 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCPH1 | microcephalin 1 |
| METTL2B | methyltransferase like 2B |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NOL10 | nucleolar protein 10 |
| NPFFR1 | neuropeptide FF receptor 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLCD1 | phospholipase C, delta 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PYGB | phosphorylase, glycogen; brain |
| QSER1 | glutamine and serine rich 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SP1 | Sp1 transcription factor |
| SPAG1 | sperm associated antigen 1 |
| SRR | serine racemase |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TASP1 | taspase, threonine aspartase, 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMC7 | transmembrane channel-like 7 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| USB1 | U6 snRNA biogenesis 1 |
| WASF3 | WAS protein family, member 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF225 | zinc finger protein 225 |
| ZNF232 | zinc finger protein 232 |
| ZNF254 | zinc finger protein 254 |
| ZNF768 | zinc finger protein 768 |
