| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the lovastatin-2854 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ADORA1 | adenosine A1 receptor |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| ATM | ATM serine/threonine kinase |
| ATN1 | atrophin 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BDKRB2 | bradykinin receptor B2 |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CA4 | carbonic anhydrase IV |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC40 | coiled-coil domain containing 40 |
| CCDC68 | coiled-coil domain containing 68 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| COL9A2 | collagen, type IX, alpha 2 |
| CTAGE5 | CTAGE family, member 5 |
| CTBP2 | C-terminal binding protein 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| EGR1 | early growth response 1 |
| FADS2 | fatty acid desaturase 2 |
| FCMR | Fc fragment of IgM receptor |
| FDX1 | ferredoxin 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLCN | folliculin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HFE | hemochromatosis |
| HIST1H3B | histone cluster 1, H3b |
| IL6ST | interleukin 6 signal transducer |
| INHBE | inhibin, beta E |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIMK2 | LIM domain kinase 2 |
| LMNB1 | lamin B1 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MED18 | mediator complex subunit 18 |
| MEX3D | mex-3 RNA binding family member D |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NME5 | NME/NM23 family member 5 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHB11 | protocadherin beta 11 |
| PCNX | pecanex homolog (Drosophila) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RB1 | retinoblastoma 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RHOB | ras homolog family member B |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPH3A | rabphilin 3A |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SYNGR3 | synaptogyrin 3 |
| TDRKH | tudor and KH domain containing |
| TEP1 | telomerase-associated protein 1 |
| TMC6 | transmembrane channel-like 6 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANKRD40 | ankyrin repeat domain 40 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOD | apolipoprotein D |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| CASZ1 | castor zinc finger 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDK20 | cyclin-dependent kinase 20 |
| CENPO | centromere protein O |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNN2 | calponin 2 |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDAR | ectodysplasin A receptor |
| ERCC6 | excision repair cross-complementation group 6 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM184A | family with sequence similarity 184, member A |
| FGF23 | fibroblast growth factor 23 |
| FOXI1 | forkhead box I1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GPR27 | G protein-coupled receptor 27 |
| HMG20A | high mobility group 20A |
| HOXA4 | homeobox A4 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| JMJD4 | jumonji domain containing 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLK5 | kallikrein-related peptidase 5 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MATK | megakaryocyte-associated tyrosine kinase |
| METTL16 | methyltransferase like 16 |
| MFAP2 | microfibrillar-associated protein 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOL12 | nucleolar protein 12 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OTUD3 | OTU deubiquitinase 3 |
| PC | pyruvate carboxylase |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRAMEF11 | PRAME family member 11 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPL10L | ribosomal protein L10-like |
| S100A4 | S100 calcium binding protein A4 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SDC3 | syndecan 3 |
| SETD1A | SET domain containing 1A |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNAI2 | snail family zinc finger 2 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STX1A | syntaxin 1A (brain) |
| SUSD6 | sushi domain containing 6 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D19 | TBC1 domain family, member 19 |
| TFF2 | trefoil factor 2 |
| TLR5 | toll-like receptor 5 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM209 | transmembrane protein 209 |
| TNRC6B | trinucleotide repeat containing 6B |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWISTNB | TWIST neighbor |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF134 | zinc finger protein 134 |
| ZNF136 | zinc finger protein 136 |
| ZNF205 | zinc finger protein 205 |
| ZNF329 | zinc finger protein 329 |
| ZNF551 | zinc finger protein 551 |
| ZNF816 | zinc finger protein 816 |
