| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the lovastatin-4978 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARRB1 | arrestin, beta 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF3 | activating transcription factor 3 |
| BAX | BCL2-associated X protein |
| BMP4 | bone morphogenetic protein 4 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CABIN1 | calcineurin binding protein 1 |
| CARF | calcium responsive transcription factor |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CFHR4 | complement factor H-related 4 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLIC5 | chloride intracellular channel 5 |
| CLTA | clathrin, light chain A |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FUZ | fuzzy planar cell polarity protein |
| GAMT | guanidinoacetate N-methyltransferase |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GSPT1 | G1 to S phase transition 1 |
| HIRA | histone cell cycle regulator |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4F | histone cluster 1, H4f |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HOMER3 | homer scaffolding protein 3 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IL5RA | interleukin 5 receptor, alpha |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| LAT2 | linker for activation of T cells family, member 2 |
| LMF2 | lipase maturation factor 2 |
| LMNB1 | lamin B1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4 | microtubule-associated protein 4 |
| MCOLN3 | mucolipin 3 |
| MED16 | mediator complex subunit 16 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG2 | NDRG family member 2 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NUCB1 | nucleobindin 1 |
| PCDH11X | protocadherin 11 X-linked |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PCNX | pecanex homolog (Drosophila) |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCE1 | phospholipase C, epsilon 1 |
| PLCG1 | phospholipase C, gamma 1 |
| PLG | plasminogen |
| PLK3 | polo-like kinase 3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RBM5 | RNA binding motif protein 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TAT | tyrosine aminotransferase |
| TBC1D19 | TBC1 domain family, member 19 |
| TEP1 | telomerase-associated protein 1 |
| TFF2 | trefoil factor 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADCY7 | adenylate cyclase 7 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CDC25A | cell division cycle 25A |
| CHKB | choline kinase beta |
| CST6 | cystatin E/M |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNBL1 | catenin, beta like 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELMO3 | engulfment and cell motility 3 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO22 | F-box protein 22 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AL | histone cluster 1, H2al |
| HOXC13 | homeobox C13 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA10 | integrin, alpha 10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0754 | KIAA0754 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC20 | leucine rich repeat containing 20 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NPTX1 | neuronal pentraxin I |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ONECUT2 | one cut homeobox 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLL | polymerase (DNA directed), lambda |
| PROCR | protein C receptor, endothelial |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RNF39 | ring finger protein 39 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIX1 | SIX homeobox 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM242 | transmembrane protein 242 |
| TMEM51 | transmembrane protein 51 |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UPK3B | uroplakin 3B |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF136 | zinc finger protein 136 |
| ZNF14 | zinc finger protein 14 |
| ZNF16 | zinc finger protein 16 |
| ZNF219 | zinc finger protein 219 |
| ZNF282 | zinc finger protein 282 |
| ZNF304 | zinc finger protein 304 |
| ZNF329 | zinc finger protein 329 |
| ZNF34 | zinc finger protein 34 |
| ZNF747 | zinc finger protein 747 |
| ZNF804A | zinc finger protein 804A |
