low-density lipoprotein particle Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. (Gene Ontology, GO_0034362)
External Link http://amigo.geneontology.org/amigo/term/GO:0034362
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Genes

7 proteins localized to the low-density lipoprotein particle cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOE apolipoprotein E
APOM apolipoprotein M
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
SELENOS selenoprotein S