low-density lipoprotein particle Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. (Gene Ontology, GO_0034362)
External Link http://amigo.geneontology.org/amigo/term/GO:0034362
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Genes

10 proteins localized to the low-density lipoprotein particle cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOE apolipoprotein E
APOM apolipoprotein M
APP amyloid beta (A4) precursor protein
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
SELENOS selenoprotein S