lowering Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

115 genes co-occuring with the biological term lowering in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACACB acetyl-CoA carboxylase beta
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA2C adrenoceptor alpha 2C
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPTL4 angiopoietin-like 4
APLN apelin
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BACE1 beta-site APP-cleaving enzyme 1
BBC3 BCL2 binding component 3
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCNL1 cyclin L1
CD177 CD177 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CETP cholesteryl ester transfer protein, plasma
CLCA1 chloride channel accessory 1
CTSD cathepsin D
CXCL8 chemokine (C-X-C motif) ligand 8
CYLD cylindromatosis (turban tumor syndrome)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DEFB103B defensin, beta 103B
ERCC6L excision repair cross-complementation group 6-like
ESR1 estrogen receptor 1
ETV6 ets variant 6
FABP4 fatty acid binding protein 4, adipocyte
FBXO7 F-box protein 7
FGB fibrinogen beta chain
FGF21 fibroblast growth factor 21
G6PD glucose-6-phosphate dehydrogenase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GHRL ghrelin/obestatin prepropeptide
GIPC1 GIPC PDZ domain containing family, member 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTM2 glutathione S-transferase mu 2 (muscle)
HAMP hepcidin antimicrobial peptide
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL6 interleukin 6
INS insulin
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF6 kinesin family member 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LDLR low density lipoprotein receptor
LEKR1 leucine, glutamate and lysine rich 1
LIPC lipase, hepatic
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYRM1 LYR motif containing 1
LYZ lysozyme
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MCOLN2 mucolipin 2
MIR203A microRNA 203a
MIR320A microRNA 320a
MIR494 microRNA 494
MSH6 mutS homolog 6
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NKX3-1 NK3 homeobox 1
NPY neuropeptide Y
PCSK9 proprotein convertase subtilisin/kexin type 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PPARA peroxisome proliferator-activated receptor alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCD protein kinase C, delta
PTCD3 pentatricopeptide repeat domain 3
PTH parathyroid hormone
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RUNX1 runt-related transcription factor 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP2 secreted frizzled-related protein 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TAS2R50 taste receptor, type 2, member 50
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TTN titin
TXN thioredoxin
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VAMP8 vesicle-associated membrane protein 8
WNT5A wingless-type MMTV integration site family, member 5A