| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the loxapine-1516 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADD2 | adducin 2 (beta) |
| AGTR1 | angiotensin II receptor, type 1 |
| APOM | apolipoprotein M |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARG1 | arginase 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATXN2L | ataxin 2-like |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CD22 | CD22 molecule |
| CD34 | CD34 molecule |
| CDC25A | cell division cycle 25A |
| CDK18 | cyclin-dependent kinase 18 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC11A | C-type lectin domain family 11, member A |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX4 | distal-less homeobox 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| DRICH1 | aspartate-rich 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EFNB3 | ephrin-B3 |
| ELL | elongation factor RNA polymerase II |
| EPS8L1 | EPS8-like 1 |
| FAM49B | family with sequence similarity 49, member B |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGF9 | fibroblast growth factor 9 |
| FLOT1 | flotillin 1 |
| FOXG1 | forkhead box G1 |
| GPATCH3 | G patch domain containing 3 |
| HFE | hemochromatosis |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HOMER3 | homer scaffolding protein 3 |
| HR | hair growth associated |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRS2 | insulin receptor substrate 2 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| JADE2 | jade family PHD finger 2 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KRT17 | keratin 17, type I |
| KRT83 | keratin 83, type II |
| LAT2 | linker for activation of T cells family, member 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MARCO | macrophage receptor with collagenous structure |
| NLRP3 | NLR family, pyrin domain containing 3 |
| PALM | paralemmin |
| PLK3 | polo-like kinase 3 |
| POLL | polymerase (DNA directed), lambda |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PURG | purine-rich element binding protein G |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAFB | scaffold attachment factor B |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SFRP4 | secreted frizzled-related protein 4 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYNJ2 | synaptojanin 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TDRKH | tudor and KH domain containing |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIMELESS | timeless circadian clock |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TWISTNB | TWIST neighbor |
| TXNL4A | thioredoxin-like 4A |
| USP34 | ubiquitin specific peptidase 34 |
| UTRN | utrophin |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF551 | zinc finger protein 551 |
| ZNF614 | zinc finger protein 614 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADM | adrenomedullin |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ATG2A | autophagy related 2A |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC88C | coiled-coil domain containing 88C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDK3 | cyclin-dependent kinase 3 |
| CDK8 | cyclin-dependent kinase 8 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRYL1 | crystallin, lambda 1 |
| CTSF | cathepsin F |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EPPK1 | epiplakin 1 |
| F2R | coagulation factor II (thrombin) receptor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM131A | family with sequence similarity 131, member A |
| FBRS | fibrosin |
| FBXO31 | F-box protein 31 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GPX2 | glutathione peroxidase 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| HOOK1 | hook microtubule-tethering protein 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KAT2B | K(lysine) acetyltransferase 2B |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL25 | kelch-like family member 25 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| LYRM9 | LYR motif containing 9 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCOLN1 | mucolipin 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1D | myosin ID |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OSMR | oncostatin M receptor |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PODXL2 | podocalyxin-like 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PROCR | protein C receptor, endothelial |
| QSER1 | glutamine and serine rich 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF31 | ring finger protein 31 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| S100A4 | S100 calcium binding protein A4 |
| SDC3 | syndecan 3 |
| SECISBP2 | SECIS binding protein 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SIX1 | SIX homeobox 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SP1 | Sp1 transcription factor |
| STBD1 | starch binding domain 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX19 | T-box 19 |
| TFF2 | trefoil factor 2 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM121 | transmembrane protein 121 |
| TRAIP | TRAF interacting protein |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TSPYL2 | TSPY-like 2 |
| WDR25 | WD repeat domain 25 |
| XAB2 | XPA binding protein 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF35 | zinc finger protein 35 |
| ZNF623 | zinc finger protein 623 |
| ZNF668 | zinc finger protein 668 |
