| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the lumicolchicine-3254 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACVR1B | activin A receptor, type IB |
| AGO4 | argonaute RISC catalytic component 4 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ART1 | ADP-ribosyltransferase 1 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASPH | aspartate beta-hydroxylase |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C3 | complement component 3 |
| CALB1 | calbindin 1, 28kDa |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CDC25A | cell division cycle 25A |
| CDIP1 | cell death-inducing p53 target 1 |
| CENPO | centromere protein O |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CST4 | cystatin S |
| CYTH1 | cytohesin 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| ECE1 | endothelin converting enzyme 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ERP44 | endoplasmic reticulum protein 44 |
| ETV5 | ets variant 5 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM120C | family with sequence similarity 120C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCMR | Fc fragment of IgM receptor |
| FHIT | fragile histidine triad |
| FRMD4B | FERM domain containing 4B |
| FSCN1 | fascin actin-bundling protein 1 |
| GK | glycerol kinase |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HN1L | hematological and neurological expressed 1-like |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAGEA5 | melanoma antigen family A5 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MDM4 | MDM4, p53 regulator |
| MED28 | mediator complex subunit 28 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MST1L | macrophage stimulating 1-like |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NGDN | neuroguidin, EIF4E binding protein |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OR7A5 | olfactory receptor, family 7, subfamily A, member 5 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCD1 | phospholipase C, delta 1 |
| PLTP | phospholipid transfer protein |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| RAB6A | RAB6A, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBM19 | RNA binding motif protein 19 |
| RHEB | Ras homolog enriched in brain |
| RHOH | ras homolog family member H |
| RPL10L | ribosomal protein L10-like |
| RRBP1 | ribosome binding protein 1 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC35E2 | solute carrier family 35, member E2 |
| SSBP3 | single stranded DNA binding protein 3 |
| STC1 | stanniocalcin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNRG | synergin, gamma |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UBTD1 | ubiquitin domain containing 1 |
| UTRN | utrophin |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| AES | amino-terminal enhancer of split |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB1 | arrestin, beta 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNO | cyclin O |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| COL4A5 | collagen, type IV, alpha 5 |
| COQ4 | coenzyme Q4 |
| CORO2A | coronin, actin binding protein, 2A |
| CSTA | cystatin A (stefin A) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EFNA3 | ephrin-A3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERCC4 | excision repair cross-complementation group 4 |
| FAAH | fatty acid amide hydrolase |
| FADS2 | fatty acid desaturase 2 |
| FBXO22 | F-box protein 22 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FKBPL | FK506 binding protein like |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLI3 | GLI family zinc finger 3 |
| GPX2 | glutathione peroxidase 2 |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HOXC10 | homeobox C10 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA1L | heat shock 70kDa protein 1-like |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0513 | KIAA0513 |
| LAMA5 | laminin, alpha 5 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTD1 | mbt domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL2B | methyltransferase like 2B |
| MFAP2 | microfibrillar-associated protein 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHA9 | protocadherin alpha 9 |
| PLA2G10 | phospholipase A2, group X |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PP14571 | uncharacterized LOC100130449 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RWDD3 | RWD domain containing 3 |
| SECTM1 | secreted and transmembrane 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3 | stromal antigen 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TDRD1 | tudor domain containing 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF160 | zinc finger protein 160 |
| ZNF282 | zinc finger protein 282 |
| ZNF329 | zinc finger protein 329 |
| ZNF652 | zinc finger protein 652 |
| ZNF778 | zinc finger protein 778 |