| Dataset | Guide to Pharmacology Chemical Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (chemical) |
| Description | An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_73044) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2897 |
| Similar Terms | |
| Downloads & Tools |
1 receptors of the lumiracoxib ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
| Symbol | Name |
|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
