lung development Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. (Gene Ontology, GO_0030324)
External Link http://amigo.geneontology.org/amigo/term/GO_0030324
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Genes

34 genes participating in the lung development biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
BAG6 BCL2-associated athanogene 6
BMP4 bone morphogenetic protein 4
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DNAAF1 dynein, axonemal, assembly factor 1
ERRFI1 ERBB receptor feedback inhibitor 1
FGF10 fibroblast growth factor 10
FGF7 fibroblast growth factor 7
FGF9 fibroblast growth factor 9
FGFR2 fibroblast growth factor receptor 2
FOXF1 forkhead box F1
FOXJ1 forkhead box J1
GLI2 GLI family zinc finger 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LOXL3 lysyl oxidase-like 3
NKX2-1 NK2 homeobox 1
NPHP3 nephronophthisis 3 (adolescent)
PDPN podoplanin
PHF14 PHD finger protein 14
PKD1 polycystic kidney disease 1 (autosomal dominant)
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PROX1 prospero homeobox 1
RCAN3 RCAN family member 3
SHH sonic hedgehog
SOX11 SRY (sex determining region Y)-box 11
STRA6 stimulated by retinoic acid 6
TCF21 transcription factor 21
VEGFA vascular endothelial growth factor A
WNT11 wingless-type MMTV integration site family, member 11
WNT7B wingless-type MMTV integration site family, member 7B
ZIC3 Zic family member 3