lupus nephritis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). (Experimental Factor Ontology, EFO_0005761)
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Genes

10 genes associated with the disease lupus nephritis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
IL18 interleukin 18
PDCD1 programmed cell death 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
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