luteolin-3379 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the luteolin-3379 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
APOLD1 apolipoprotein L domain containing 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CATSPERB catsper channel auxiliary subunit beta
CD47 CD47 molecule
CD53 CD53 molecule
CD70 CD70 molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEL carboxyl ester lipase
CEP41 centrosomal protein 41kDa
CLCN7 chloride channel, voltage-sensitive 7
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CTRC chymotrypsin C (caldecrin)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFNB31 deafness, autosomal recessive 31
DIEXF digestive organ expansion factor homolog (zebrafish)
DKFZP434C153 DKFZP434C153 protein
DNASE1 deoxyribonuclease I
ECM1 extracellular matrix protein 1
EGR1 early growth response 1
EGR3 early growth response 3
ERCC2 excision repair cross-complementation group 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBXL8 F-box and leucine-rich repeat protein 8
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOSL1 FOS-like antigen 1
FRMD4A FERM domain containing 4A
FSTL1 follistatin-like 1
GPER1 G protein-coupled estrogen receptor 1
GPR87 G protein-coupled receptor 87
GUCA1B guanylate cyclase activator 1B (retina)
HHAT hedgehog acyltransferase
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BI histone cluster 1, H2bi
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HMGN5 high mobility group nucleosome binding domain 5
HP haptoglobin
IFI6 interferon, alpha-inducible protein 6
IL2RG interleukin 2 receptor, gamma
IRF4 interferon regulatory factor 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCTD13 potassium channel tetramerization domain containing 13
KRT15 keratin 15, type I
LAMB4 laminin, beta 4
LGALS8 lectin, galactoside-binding, soluble, 8
LIF leukemia inhibitory factor
LMX1B LIM homeobox transcription factor 1, beta
LOC157562 uncharacterized LOC157562
LRRC17 leucine rich repeat containing 17
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGAM maltase-glucoamylase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
N4BP2L2 NEDD4 binding protein 2-like 2
NOV nephroblastoma overexpressed
NSUN6 NOP2/Sun domain family, member 6
OSBPL7 oxysterol binding protein-like 7
OTOR otoraplin
PAQR6 progestin and adipoQ receptor family member VI
PCNXL2 pecanex-like 2 (Drosophila)
PCYOX1L prenylcysteine oxidase 1 like
PEX3 peroxisomal biogenesis factor 3
PLCB2 phospholipase C, beta 2
PTX3 pentraxin 3, long
RGS5 regulator of G-protein signaling 5
RSL1D1 ribosomal L1 domain containing 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMIM7 small integral membrane protein 7
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STEAP4 STEAP family member 4
TECTA tectorin alpha
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TMEM144 transmembrane protein 144
TNPO2 transportin 2
TPP1 tripeptidyl peptidase I
TREX1 three prime repair exonuclease 1
TRIM66 tripartite motif containing 66
UBA7 ubiquitin-like modifier activating enzyme 7
UCN urocortin
XAF1 XIAP associated factor 1
ZBED4 zinc finger, BED-type containing 4
ZEB1 zinc finger E-box binding homeobox 1
ZNF862 zinc finger protein 862
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ARMC6 armadillo repeat containing 6
ARMCX5 armadillo repeat containing, X-linked 5
ATAD2B ATPase family, AAA domain containing 2B
B9D2 B9 protein domain 2
BAHCC1 BAH domain and coiled-coil containing 1
BEX4 brain expressed, X-linked 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C19ORF73 chromosome 19 open reading frame 73
C1ORF112 chromosome 1 open reading frame 112
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMTA1 calmodulin binding transcription activator 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC9 coiled-coil domain containing 9
CCNE2 cyclin E2
CCP110 centriolar coiled coil protein 110kDa
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPI centromere protein I
CEP97 centrosomal protein 97kDa
CHKA choline kinase alpha
CHML choroideremia-like (Rab escort protein 2)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CRBN cereblon
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGKD diacylglycerol kinase, delta 130kDa
DIXDC1 DIX domain containing 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGLN3 egl-9 family hypoxia-inducible factor 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHA4 EPH receptor A4
FKBP5 FK506 binding protein 5
FLJ22184
FMO4 flavin containing monooxygenase 4
GDAP1 ganglioside induced differentiation associated protein 1
GLCE glucuronic acid epimerase
GPR27 G protein-coupled receptor 27
GTF2IRD1 GTF2I repeat domain containing 1
GTPBP8 GTP-binding protein 8 (putative)
HSPA2 heat shock 70kDa protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFT88 intraflagellar transport 88
IL4R interleukin 4 receptor
INTS6 integrator complex subunit 6
KAT2A K(lysine) acetyltransferase 2A
KCTD20 potassium channel tetramerization domain containing 20
KIZ kizuna centrosomal protein
KLF11 Kruppel-like factor 11
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LRRC20 leucine rich repeat containing 20
LYPD1 LY6/PLAUR domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MEPCE methylphosphate capping enzyme
MMP9 matrix metallopeptidase 9
MSX1 msh homeobox 1
MUM1 melanoma associated antigen (mutated) 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PCTP phosphatidylcholine transfer protein
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTPN3 protein tyrosine phosphatase, non-receptor type 3
REEP1 receptor accessory protein 1
RNF126P1 ring finger protein 126 pseudogene 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SFMBT1 Scm-like with four mbt domains 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPC25 SPC25, NDC80 kinetochore complex component
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TMEM121 transmembrane protein 121
TNS2 tensin 2
TRAF5 TNF receptor-associated factor 5
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAV3 vav 3 guanine nucleotide exchange factor
WDR70 WD repeat domain 70
ZFP69B ZFP69 zinc finger protein B
ZIC1 Zic family member 1
ZNF248 zinc finger protein 248
ZNF253 zinc finger protein 253
ZNF586 zinc finger protein 586
ZNF675 zinc finger protein 675
ZXDC ZXD family zinc finger C