| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the lymecycline-2953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APOM | apolipoprotein M |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATN1 | atrophin 1 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BPI | bactericidal/permeability-increasing protein |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CD180 | CD180 molecule |
| CD22 | CD22 molecule |
| CDC25C | cell division cycle 25C |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CLTA | clathrin, light chain A |
| COL11A2 | collagen, type XI, alpha 2 |
| CUX1 | cut-like homeobox 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DES | desmin |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHB6 | EPH receptor B6 |
| ETV1 | ets variant 1 |
| EXOC7 | exocyst complex component 7 |
| GALK1 | galactokinase 1 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR153 | G protein-coupled receptor 153 |
| GPR21 | G protein-coupled receptor 21 |
| HDAC11 | histone deacetylase 11 |
| HDAC7 | histone deacetylase 7 |
| HFE | hemochromatosis |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H4E | histone cluster 1, H4e |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KHK | ketohexokinase (fructokinase) |
| LRRC23 | leucine rich repeat containing 23 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MEFV | Mediterranean fever |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MID1 | midline 1 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MR1 | major histocompatibility complex, class I-related |
| MVK | mevalonate kinase |
| MYOZ3 | myozenin 3 |
| NOP16 | NOP16 nucleolar protein |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NRF1 | nuclear respiratory factor 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OXTR | oxytocin receptor |
| PADI2 | peptidyl arginine deiminase, type II |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta |
| PLAA | phospholipase A2-activating protein |
| PLCD1 | phospholipase C, delta 1 |
| PLCG1 | phospholipase C, gamma 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTK2B | protein tyrosine kinase 2 beta |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB6A | RAB6A, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RAP1GAP | RAP1 GTPase activating protein |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| ST5 | suppression of tumorigenicity 5 |
| STAB1 | stabilin 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| THBS3 | thrombospondin 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| WDR78 | WD repeat domain 78 |
| WWC1 | WW and C2 domain containing 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF428 | zinc finger protein 428 |
| ZNF512B | zinc finger protein 512B |
| ZNF549 | zinc finger protein 549 |
| ZNF695 | zinc finger protein 695 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADRB2 | adrenoceptor beta 2, surface |
| AGO1 | argonaute RISC catalytic component 1 |
| AGO3 | argonaute RISC catalytic component 3 |
| AHR | aryl hydrocarbon receptor |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNJ | cyclin J |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD69 | CD69 molecule |
| CD9 | CD9 molecule |
| CENPJ | centromere protein J |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC7A | C-type lectin domain family 7, member A |
| CLK1 | CDC-like kinase 1 |
| COQ3 | coenzyme Q3 methyltransferase |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNMBP | dynamin binding protein |
| ECM1 | extracellular matrix protein 1 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM184A | family with sequence similarity 184, member A |
| FAM192A | family with sequence similarity 192, member A |
| FHIT | fragile histidine triad |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GID4 | GID complex subunit 4 |
| GK3P | glycerol kinase 3 pseudogene |
| GPR85 | G protein-coupled receptor 85 |
| GRAMD1B | GRAM domain containing 1B |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| INHBE | inhibin, beta E |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IREB2 | iron-responsive element binding protein 2 |
| KIF13B | kinesin family member 13B |
| KIF18A | kinesin family member 18A |
| LINS | lines homolog (Drosophila) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP1S | microtubule-associated protein 1S |
| MCRS1 | microspherule protein 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTCP1 | mature T-cell proliferation 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NABP2 | nucleic acid binding protein 2 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDZD7 | PDZ domain containing 7 |
| PHACTR1 | phosphatase and actin regulator 1 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTH2R | parathyroid hormone 2 receptor |
| PTX3 | pentraxin 3, long |
| RARS | arginyl-tRNA synthetase |
| RGS13 | regulator of G-protein signaling 13 |
| RNF11 | ring finger protein 11 |
| RNF121 | ring finger protein 121 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCRN3 | secernin 3 |
| SFXN1 | sideroflexin 1 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPIDR | scaffolding protein involved in DNA repair |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM115 | transmembrane protein 115 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| UBQLN4 | ubiquilin 4 |
| USP32 | ubiquitin specific peptidase 32 |
| VNN2 | vanin 2 |
| WDR13 | WD repeat domain 13 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF10 | zinc finger protein 10 |
| ZNF443 | zinc finger protein 443 |
| ZNF83 | zinc finger protein 83 |
| ZNF862 | zinc finger protein 862 |
