| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the lymecycline-3514 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AIF1 | allograft inflammatory factor 1 |
| AJAP1 | adherens junctions associated protein 1 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AMACR | alpha-methylacyl-CoA racemase |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP1 | bone morphogenetic protein 1 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C1QB | complement component 1, q subcomponent, B chain |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CARTPT | CART prepropeptide |
| CCNJL | cyclin J-like |
| CD83 | CD83 molecule |
| CD8A | CD8a molecule |
| CDC25C | cell division cycle 25C |
| CFHR4 | complement factor H-related 4 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EDAR | ectodysplasin A receptor |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGL1 | fibrinogen-like 1 |
| FRY | furry homolog (Drosophila) |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLS | glutaminase |
| GPR3 | G protein-coupled receptor 3 |
| GRK4 | G protein-coupled receptor kinase 4 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HP | haptoglobin |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL11 | interleukin 11 |
| ITM2C | integral membrane protein 2C |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA1324 | KIAA1324 |
| KIFC3 | kinesin family member C3 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MX2 | MX dynamin-like GTPase 2 |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEUROG1 | neurogenin 1 |
| NHLH2 | nescient helix loop helix 2 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPFF | neuropeptide FF-amide peptide precursor |
| OGFR | opioid growth factor receptor |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PGR | progesterone receptor |
| PLLP | plasmolipin |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR5 | proline rich 5 (renal) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAB3B | RAB3B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RND1 | Rho family GTPase 1 |
| RPS3A | ribosomal protein S3A |
| RRAGD | Ras-related GTP binding D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLA | Src-like-adaptor |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMCP | sperm mitochondria-associated cysteine-rich protein |
| SPRR1A | small proline-rich protein 1A |
| TGFB1 | transforming growth factor, beta 1 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM10 | tripartite motif containing 10 |
| UBOX5 | U-box domain containing 5 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WSCD1 | WSC domain containing 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF230 | zinc finger protein 230 |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ABHD17B | abhydrolase domain containing 17B |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC186 | coiled-coil domain containing 186 |
| CD302 | CD302 molecule |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLDN15 | claudin 15 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSTA | cystatin A (stefin A) |
| CTAGE9 | CTAGE family, member 9 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EAF2 | ELL associated factor 2 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM63A | family with sequence similarity 63, member A |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLNC | filamin C, gamma |
| FRK | fyn-related Src family tyrosine kinase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALK1 | galactokinase 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLCE | glucuronic acid epimerase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIST1H2AM | histone cluster 1, H2am |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF7 | interferon regulatory factor 7 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM8 | lysine (K)-specific demethylase 8 |
| LAMB1 | laminin, beta 1 |
| LINS | lines homolog (Drosophila) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC390998 | ribosomal protein L10 pseudogene |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCC | mutated in colorectal cancers |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARPBP | PARP1 binding protein |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POPDC3 | popeye domain containing 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF170 | ring finger protein 170 |
| RPL10L | ribosomal protein L10-like |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SP1 | Sp1 transcription factor |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STIM1 | stromal interaction molecule 1 |
| STON1 | stonin 1 |
| STX5 | syntaxin 5 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMEM104 | transmembrane protein 104 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM25 | tripartite motif containing 25 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF480 | zinc finger protein 480 |
| ZNF510 | zinc finger protein 510 |
| ZNF606 | zinc finger protein 606 |
| ZNF652 | zinc finger protein 652 |
