| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the lymecycline-5994 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AIM1L | absent in melanoma 1-like |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATG10 | autophagy related 10 |
| ATN1 | atrophin 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BIN1 | bridging integrator 1 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CCDC121 | coiled-coil domain containing 121 |
| CD58 | CD58 molecule |
| CD86 | CD86 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CLEC4M | C-type lectin domain family 4, member M |
| CPA4 | carboxypeptidase A4 |
| CPQ | carboxypeptidase Q |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK4 | docking protein 4 |
| DRD2 | dopamine receptor D2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ESR1 | estrogen receptor 1 |
| ETV6 | ets variant 6 |
| EXPH5 | exophilin 5 |
| FAM134B | family with sequence similarity 134, member B |
| GAB1 | GRB2-associated binding protein 1 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| H2AFX | H2A histone family, member X |
| HAMP | hepcidin antimicrobial peptide |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HHLA1 | HERV-H LTR-associating 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIAA0754 | KIAA0754 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT23 | keratin 23, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMC2 | laminin, gamma 2 |
| LEFTY1 | left-right determination factor 1 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMF2 | lipase maturation factor 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK11 | mitogen-activated protein kinase 11 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYO15A | myosin XVA |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYT1 | myelin transcription factor 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NGLY1 | N-glycanase 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PCDHB8 | protocadherin beta 8 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PEX19 | peroxisomal biogenesis factor 19 |
| PHF1 | PHD finger protein 1 |
| PLXDC1 | plexin domain containing 1 |
| POMC | proopiomelanocortin |
| PVRL3 | poliovirus receptor-related 3 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RASAL2 | RAS protein activator like 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SCN1A | sodium channel, voltage gated, type I alpha subunit |
| SDC2 | syndecan 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SPTB | spectrin, beta, erythrocytic |
| SUGP1 | SURP and G patch domain containing 1 |
| TBX6 | T-box 6 |
| TMEM19 | transmembrane protein 19 |
| TMEM254 | transmembrane protein 254 |
| TNIK | TRAF2 and NCK interacting kinase |
| TSC22D2 | TSC22 domain family, member 2 |
| TSHR | thyroid stimulating hormone receptor |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WLS | wntless Wnt ligand secretion mediator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF154 | zinc finger protein 154 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARSB | arylsulfatase B |
| B9D2 | B9 protein domain 2 |
| BAGE | B melanoma antigen |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CARTPT | CART prepropeptide |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC186 | coiled-coil domain containing 186 |
| CD82 | CD82 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CXXC4 | CXXC finger protein 4 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOCK1 | dedicator of cytokinesis 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| FAM204A | family with sequence similarity 204, member A |
| FLCN | folliculin |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GMPR | guanosine monophosphate reductase |
| GPC3 | glypican 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXD11 | homeobox D11 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT22 | intraflagellar transport 22 |
| IFT81 | intraflagellar transport 81 |
| IL17RA | interleukin 17 receptor A |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IPO8 | importin 8 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0894 | KIAA0894 protein |
| KIAA1456 | KIAA1456 |
| KLF2 | Kruppel-like factor 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MBTD1 | mbt domain containing 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MSX1 | msh homeobox 1 |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGPEP1 | pyroglutamyl-peptidase I |
| POLH | polymerase (DNA directed), eta |
| POMT2 | protein-O-mannosyltransferase 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF43 | ring finger protein 43 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCHIP1 | schwannomin interacting protein 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SHB | Src homology 2 domain containing adaptor protein B |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP1 | Sp1 transcription factor |
| SPRR2B | small proline-rich protein 2B |
| TBX19 | T-box 19 |
| TLR5 | toll-like receptor 5 |
| TMEM180 | transmembrane protein 180 |
| TMEM183A | transmembrane protein 183A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| UPP1 | uridine phosphorylase 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT2 | xylosyltransferase II |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF180 | zinc finger protein 180 |
| ZNF329 | zinc finger protein 329 |
| ZNF365 | zinc finger protein 365 |
| ZNF573 | zinc finger protein 573 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
