| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the lymecycline-7291 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ASTN2 | astrotactin 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C8A | complement component 8, alpha polypeptide |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CAV2 | caveolin 2 |
| CCNK | cyclin K |
| CCNO | cyclin O |
| CD28 | CD28 molecule |
| CD58 | CD58 molecule |
| CIB2 | calcium and integrin binding family member 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DENND2A | DENN/MADD domain containing 2A |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAH2 | dynein, axonemal, heavy chain 2 |
| DUSP8 | dual specificity phosphatase 8 |
| EED | embryonic ectoderm development |
| FA2H | fatty acid 2-hydroxylase |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FLJ11292 | |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXN2 | forkhead box N2 |
| GPR161 | G protein-coupled receptor 161 |
| GYPB | glycophorin B (MNS blood group) |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HOXB6 | homeobox B6 |
| HRH2 | histamine receptor H2 |
| INADL | InaD-like (Drosophila) |
| IRF5 | interferon regulatory factor 5 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KLHL22 | kelch-like family member 22 |
| KRT34 | keratin 34, type I |
| LAMA4 | laminin, alpha 4 |
| LIMK2 | LIM domain kinase 2 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC399491 | |
| LRRC61 | leucine rich repeat containing 61 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MEP1B | meprin A, beta |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MLH3 | mutL homolog 3 |
| MTCP1 | mature T-cell proliferation 1 |
| NFASC | neurofascin |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NRCAM | neuronal cell adhesion molecule |
| NRTN | neurturin |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSBP2 | oxysterol binding protein 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLXNB3 | plexin B3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RNF39 | ring finger protein 39 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| TXLNG | taxilin gamma |
| UNC13A | unc-13 homolog A (C. elegans) |
| WDR25 | WD repeat domain 25 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF286A | zinc finger protein 286A |
| ZNF446 | zinc finger protein 446 |
| ZNF688 | zinc finger protein 688 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANXA10 | annexin A10 |
| APH1A | APH1A gamma secretase subunit |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARRB2 | arrestin, beta 2 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATG2B | autophagy related 2B |
| BAK1 | BCL2-antagonist/killer 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BCL9 | B-cell CLL/lymphoma 9 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5 | complement component 5 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC47 | coiled-coil domain containing 47 |
| CEP72 | centrosomal protein 72kDa |
| CHEK2 | checkpoint kinase 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ETNK2 | ethanolamine kinase 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM127B | family with sequence similarity 127, member B |
| FAM131A | family with sequence similarity 131, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPALPP1 | GPALPP motifs containing 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HDAC4 | histone deacetylase 4 |
| HIRIP3 | HIRA interacting protein 3 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KRT6A | keratin 6A, type II |
| MCM9 | minichromosome maintenance complex component 9 |
| METTL16 | methyltransferase like 16 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP13 | matrix metallopeptidase 13 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NABP2 | nucleic acid binding protein 2 |
| NBEA | neurobeachin |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PCBP4 | poly(rC) binding protein 4 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLD2 | phospholipase D2 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNX24 | sorting nexin 24 |
| STAR | steroidogenic acute regulatory protein |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TH | tyrosine hydroxylase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRABD | TraB domain containing |
| TRIM66 | tripartite motif containing 66 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP36 | ubiquitin specific peptidase 36 |
| VEGFB | vascular endothelial growth factor B |
| WDR91 | WD repeat domain 91 |
| WWC2 | WW and C2 domain containing 2 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF165 | zinc finger protein 165 |
| ZNF562 | zinc finger protein 562 |
| ZNF574 | zinc finger protein 574 |
| ZNF668 | zinc finger protein 668 |
