lymphedema Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

187 genes co-occuring with the disease lymphedema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FOXC2 forkhead box C2 2.50606
VEGFC vascular endothelial growth factor C 2.30656
FLT4 fms-related tyrosine kinase 4 2.19244
SOX18 SRY (sex determining region Y)-box 18 2.14175
CCBE1 collagen and calcium binding EGF domains 1 2.02929
PROX1 prospero homeobox 1 1.79976
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.64173
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 1.52248
GJC2 gap junction protein, gamma 2, 47kDa 1.44782
PDPN podoplanin 1.4184
CPXM1 carboxypeptidase X (M14 family), member 1 1.35768
GATA2 GATA binding protein 2 1.30794
ITGA9 integrin, alpha 9 1.26691
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.17593
MFF mitochondrial fission factor 1.1524
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 1.12277
EMILIN1 elastin microfibril interfacer 1 1.11099
HMGA2 high mobility group AT-hook 2 1.10175
FOXP2 forkhead box P2 1.09251
ALB albumin 1.08621
NRP2 neuropilin 2 1.00119
GLMN glomulin, FKBP associated protein 0.956196
KIF11 kinesin family member 11 0.925039
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.919261
SNRK SNF related kinase 0.888438
SRCIN1 SRC kinase signaling inhibitor 1 0.888029
ZCCHC14 zinc finger, CCHC domain containing 14 0.879424
SHOX short stature homeobox 0.868368
PTX3 pentraxin 3, long 0.850764
SCRT1 scratch family zinc finger 1 0.826999
CHMP1A charged multivesicular body protein 1A 0.78066
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.778613
VEGFB vascular endothelial growth factor B 0.749237
CALCRL calcitonin receptor-like 0.725716
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.708767
HBA2 hemoglobin, alpha 2 0.694301
HBA1 hemoglobin, alpha 1 0.676308
SCN10A sodium channel, voltage gated, type X alpha subunit 0.66914
EPN1 epsin 1 0.649718
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.634349
AGGF1 angiogenic factor with G patch and FHA domains 1 0.633956
PEPD peptidase D 0.62885
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.613183
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.606152
FOXC1 forkhead box C1 0.60108
NF1 neurofibromin 1 0.597181
VEGFA vascular endothelial growth factor A 0.578494
F8 coagulation factor VIII, procoagulant component 0.575383
NVL nuclear VCP-like 0.570329
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.567609
ADGRL3 adhesion G protein-coupled receptor L3 0.566831
PDHX pyruvate dehydrogenase complex, component X 0.562558
RPE ribulose-5-phosphate-3-epimerase 0.553239
CD4 CD4 molecule 0.550522
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.547419
CLEC1B C-type lectin domain family 1, member B 0.542379
SOX17 SRY (sex determining region Y)-box 17 0.533861
FLT1 fms-related tyrosine kinase 1 0.514186
GJA4 gap junction protein, alpha 4, 37kDa 0.507657
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.505739
NIPBL Nipped-B homolog (Drosophila) 0.494648
WAC WW domain containing adaptor with coiled-coil 0.485885
FAT4 FAT atypical cadherin 4 0.47753
PMF1 polyamine-modulated factor 1 0.474498
EDARADD EDAR-associated death domain 0.467306
PDCD10 programmed cell death 10 0.46466
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.463149
FOXL1 forkhead box L1 0.45447
CUL5 cullin 5 0.451078
TLR2 toll-like receptor 2 0.448064
EFNB2 ephrin-B2 0.445429
MMP8 matrix metallopeptidase 8 0.42214
PTPRB protein tyrosine phosphatase, receptor type, B 0.420266
MAML1 mastermind-like 1 (Drosophila) 0.405305
PLXNA1 plexin A1 0.404557
CD34 CD34 molecule 0.404557
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.402692
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.401572
SRY sex determining region Y 0.394118
SH2D5 SH2 domain containing 5 0.393001
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.392629
GJA1 gap junction protein, alpha 1, 43kDa 0.388538
DIO3 deiodinase, iodothyronine, type III 0.379256
SP9 Sp9 transcription factor 0.37592
IGLV9-49 immunoglobulin lambda variable 9-49 0.374068
UBTF upstream binding transcription factor, RNA polymerase I 0.372217
SP6 Sp6 transcription factor 0.371477
HAL histidine ammonia-lyase 0.369997
NCF2 neutrophil cytosolic factor 2 0.36741
PLA2G2D phospholipase A2, group IID 0.36187
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.361502
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.360395
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.358551
SCYL1 SCY1-like 1 (S. cerevisiae) 0.336144
PGF placental growth factor 0.335412
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.333583
METTL13 methyltransferase like 13 0.332487
LAX1 lymphocyte transmembrane adaptor 1 0.324823
SAMD11 sterile alpha motif domain containing 11 0.323002
KRIT1 KRIT1, ankyrin repeat containing 0.321181
PER3 period circadian clock 3 0.311739
RELN reelin 0.311377
KDR kinase insert domain receptor 0.309566
INSC inscuteable homolog (Drosophila) 0.308118
UST uronyl-2-sulfotransferase 0.302698
CHIT1 chitinase 1 (chitotriosidase) 0.301615
PARVA parvin, alpha 0.299812
NT5E 5'-nucleotidase, ecto (CD73) 0.298731
ADM adrenomedullin 0.294413
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.291539
NRP1 neuropilin 1 0.291539
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.290462
CCL21 chemokine (C-C motif) ligand 21 0.288668
IL4 interleukin 4 0.269398
TSC2 tuberous sclerosis 2 0.266203
GJC1 gap junction protein, gamma 1, 45kDa 0.253831
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.248554
INPPL1 inositol polyphosphate phosphatase-like 1 0.24715
ACTA2 actin, alpha 2, smooth muscle, aorta 0.242245
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.230755
GRAP2 GRB2-related adaptor protein 2 0.230063
VCAM1 vascular cell adhesion molecule 1 0.226952
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.224884
IL2 interleukin 2 0.222136
RORC RAR-related orphan receptor C 0.218715
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.215823
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.213367
SMAD5 SMAD family member 5 0.213283
CDH5 cadherin 5, type 2 (vascular endothelium) 0.212608
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.211934
ACRV1 acrosomal vesicle protein 1 0.211597
YME1L1 YME1-like 1 ATPase 0.205585
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.200331
CYS1 cystin 1 0.196139
ACVR1 activin A receptor, type I 0.189859
ANGPT2 angiopoietin 2 0.189551
ACOT13 acyl-CoA thioesterase 13 0.187415
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.183835
IGLL5 immunoglobulin lambda-like polypeptide 5 0.183248
LRP5 low density lipoprotein receptor-related protein 5 0.183248
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.182302
BMP2K BMP2 inducible kinase 0.180084
KITLG KIT ligand 0.179802
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.17952
NAGA N-acetylgalactosaminidase, alpha- 0.177029
PMM2 phosphomannomutase 2 0.175947
MID2 midline 2 0.175146
FGF2 fibroblast growth factor 2 (basic) 0.168148
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.167452
ADGRV1 adhesion G protein-coupled receptor V1 0.164359
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.162505
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.158778
CXCL8 chemokine (C-X-C motif) ligand 8 0.157765
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.152946
FOXO3 forkhead box O3 0.142944
CANX calnexin 0.142521
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.142457
FGFR4 fibroblast growth factor receptor 4 0.142416
CD27 CD27 molecule 0.142216
FEN1 flap structure-specific endonuclease 1 0.141823
NOD1 nucleotide-binding oligomerization domain containing 1 0.141251
UBE2K ubiquitin-conjugating enzyme E2K 0.141137
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.141055
MRAP melanocortin 2 receptor accessory protein 0.140851
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.140479
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.140205
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.140162
TLR1 toll-like receptor 1 0.139825
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.139416
ANGPT1 angiopoietin 1 0.138834
IL7 interleukin 7 0.138825
ENO1 enolase 1, (alpha) 0.138825
CYBA cytochrome b-245, alpha polypeptide 0.138761
EPX eosinophil peroxidase 0.138623
EDN1 endothelin 1 0.137465
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.13742
IL10 interleukin 10 0.134807
DLL1 delta-like 1 (Drosophila) 0.13431
RNASE3 ribonuclease, RNase A family, 3 0.133922
IFNG interferon, gamma 0.133535
SELL selectin L 0.133055
COL1A2 collagen, type I, alpha 2 0.131022
MAPK14 mitogen-activated protein kinase 14 0.130645
NOD2 nucleotide-binding oligomerization domain containing 2 0.129616
TSHR thyroid stimulating hormone receptor 0.12863
MAPK3 mitogen-activated protein kinase 3 0.128254
TLR9 toll-like receptor 9 0.126764