lymphedema Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001004
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Genes

37 genes associated with the lymphedema phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALG8 ALG8, alpha-1,3-glucosyltransferase
ANTXR2 anthrax toxin receptor 2
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCBE1 collagen and calcium binding EGF domains 1
FAT4 FAT atypical cadherin 4
FLT4 fms-related tyrosine kinase 4
FOXC2 forkhead box C2
GATA2 GATA binding protein 2
GLA galactosidase, alpha
GUSB glucuronidase, beta
HDAC8 histone deacetylase 8
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
KAT6B K(lysine) acetyltransferase 6B
KIF11 kinesin family member 11
KRAS Kirsten rat sarcoma viral oncogene homolog
LBR lamin B receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MPI mannose phosphate isomerase
NAGA N-acetylgalactosaminidase, alpha-
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RIT1 Ras-like without CAAX 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SOS1 son of sevenless homolog 1 (Drosophila)
SOX18 SRY (sex determining region Y)-box 18
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2