lymphocyte Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Any of the colorless weakly motile cells originating from stem cells and differentiating in lymphoid tissue (as of the thymus or bone marrow) that are the typical cellular elements of lymph, include the cellular mediators of immunity, and constitute 20 to 30 percent of the white blood cells of normal human blood. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000775)
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Genes

366 genes co-occuring with the biological term lymphocyte in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADA adenosine deaminase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRBK1 adrenergic, beta, receptor kinase 1
AGRP agouti related neuropeptide
AIM2 absent in melanoma 2
AKAP9 A kinase (PRKA) anchor protein 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AOC3 amine oxidase, copper containing 3
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOA4 apolipoprotein A-IV
AR androgen receptor
ARHGAP4 Rho GTPase activating protein 4
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BTLA B and T lymphocyte associated
C3 complement component 3
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CALCA calcitonin-related polypeptide alpha
CARD11 caspase recruitment domain family, member 11
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL1 chemokine (C-C motif) ligand 1
CCL17 chemokine (C-C motif) ligand 17
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL21 chemokine (C-C motif) ligand 21
CCL24 chemokine (C-C motif) ligand 24
CCL5 chemokine (C-C motif) ligand 5
CCND3 cyclin D3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD160 CD160 molecule
CD163 CD163 molecule
CD19 CD19 molecule
CD1B CD1b molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD5 CD5 molecule
CD52 CD52 molecule
CD53 CD53 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CD8A CD8a molecule
CD93 CD93 molecule
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CREB1 cAMP responsive element binding protein 1
CRISP3 cysteine-rich secretory protein 3
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSL cathepsin L
CTSW cathepsin W
CUL1 cullin 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYTIP cytohesin 1 interacting protein
DCLRE1C DNA cross-link repair 1C
DOCK2 dedicator of cytokinesis 2
DPP4 dipeptidyl-peptidase 4
DPP8 dipeptidyl-peptidase 8
DPP9 dipeptidyl-peptidase 9
DPYSL2 dihydropyrimidinase-like 2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
DUSP2 dual specificity phosphatase 2
EBAG9 estrogen receptor binding site associated, antigen, 9
EDC4 enhancer of mRNA decapping 4
EDN1 endothelin 1
EIF3A eukaryotic translation initiation factor 3, subunit A
ELANE elastase, neutrophil expressed
ELMO1 engulfment and cell motility 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FERMT3 fermitin family member 3
FGF2 fibroblast growth factor 2 (basic)
FMR1 fragile X mental retardation 1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GCSAM germinal center-associated, signaling and motility
GIMAP1 GTPase, IMAP family member 1
GIMAP4 GTPase, IMAP family member 4
GIMAP5 GTPase, IMAP family member 5
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPX4 glutathione peroxidase 4
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GSK3B glycogen synthase kinase 3 beta
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AFX H2A histone family, member X
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCST hematopoietic cell signal transducer
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HOXB4 homeobox B4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IDO1 indoleamine 2,3-dioxygenase 1
IFI44L interferon-induced protein 44-like
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFNL4 interferon, lambda 4 (gene/pseudogene)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL16 interleukin 16
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IQGAP1 IQ motif containing GTPase activating protein 1
IRF7 interferon regulatory factor 7
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB7 integrin, beta 7
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
JUN jun proto-oncogene
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDR kinase insert domain receptor
KIAA0430 KIAA0430
KLK6 kallikrein-related peptidase 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMP2 lysosomal-associated membrane protein 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LIF leukemia inhibitory factor
LY6E lymphocyte antigen 6 complex, locus E
LY6K lymphocyte antigen 6 complex, locus K
LY75 lymphocyte antigen 75
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEC2 melanoma antigen family C2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MCM2 minichromosome maintenance complex component 2
MECP2 methyl CpG binding protein 2
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR150 microRNA 150
MIR21 microRNA 21
MKI67 marker of proliferation Ki-67
MLANA melan-A
MME membrane metallo-endopeptidase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MPZL2 myelin protein zero-like 2
MRC1 mannose receptor, C type 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUM1 melanoma associated antigen (mutated) 1
MYH9 myosin, heavy chain 9, non-muscle
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NCR3 natural cytotoxicity triggering receptor 3
NEU1 sialidase 1 (lysosomal sialidase)
NGF nerve growth factor (beta polypeptide)
NHEJ1 nonhomologous end-joining factor 1
NOTCH1 notch 1
NOTCH2 notch 2
NPAT nuclear protein, ataxia-telangiectasia locus
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
OGG1 8-oxoguanine DNA glycosylase
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORAI1 ORAI calcium release-activated calcium modulator 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PAX5 paired box 5
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLAC1 placenta-specific 1
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PLEK2 pleckstrin 2
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMEL premelanosome protein
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM1 PR domain containing 1, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PRLR prolactin receptor
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PURA purine-rich element binding protein A
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PVRL3 poliovirus receptor-related 3
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RFXAP regulatory factor X-associated protein
RHOA ras homolog family member A
RLN2 relaxin 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RORC RAR-related orphan receptor C
RPSA ribosomal protein SA
S1PR1 sphingosine-1-phosphate receptor 1
S1PR4 sphingosine-1-phosphate receptor 4
S1PR5 sphingosine-1-phosphate receptor 5
SATB1 SATB homeobox 1
SCGB2A2 secretoglobin, family 2A, member 2
SELE selectin E
SELK selenoprotein K
SELL selectin L
SELPLG selectin P ligand
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGPL1 sphingosine-1-phosphate lyase 1
SH2D1A SH2 domain containing 1A
SH2D2A SH2 domain containing 2A
SHARPIN SHANK-associated RH domain interactor
SHH sonic hedgehog
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIVA1 SIVA1, apoptosis-inducing factor
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF7 SLAM family member 7
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SPNS2 spinster homolog 2 (Drosophila)
SPP1 secreted phosphoprotein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAB1 stabilin 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
STX11 syntaxin 11
TAAR1 trace amine associated receptor 1
TAPBP TAP binding protein (tapasin)
TBX21 T-box 21
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEC tec protein tyrosine kinase
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TMED1 transmembrane emp24 protein transport domain containing 1
TNC tenascin C
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53 tumor protein p53
TPBG trophoblast glycoprotein
TPI1 triosephosphate isomerase 1
TRD T cell receptor delta locus
TRIM22 tripartite motif containing 22
TRIM5 tripartite motif containing 5
TTK TTK protein kinase
TXN thioredoxin
TYK2 tyrosine kinase 2
TYR tyrosinase
TYROBP TYRO protein tyrosine kinase binding protein
USP36 ubiquitin specific peptidase 36
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VPREB3 pre-B lymphocyte 3
WAS Wiskott-Aldrich syndrome
WT1 Wilms tumor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF304 zinc finger protein 304