lynestrenol-1537 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lynestrenol-1537 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADARB1 adenosine deaminase, RNA-specific, B1
AREG amphiregulin
ARG1 arginase 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC11A C-type lectin domain family 11, member A
CNTNAP1 contactin associated protein 1
DDIT3 DNA-damage-inducible transcript 3
DOCK5 dedicator of cytokinesis 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR1 early growth response 1
EGR3 early growth response 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV5 ets variant 5
FAM46C family with sequence similarity 46, member C
FNDC3A fibronectin type III domain containing 3A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FRK fyn-related Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HEMK1 HemK methyltransferase family member 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2AE histone cluster 1, H2ae
HIST1H2AK histone cluster 1, H2ak
HIST1H2BC histone cluster 1, H2bc
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIF1C kinesin family member 1C
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
LOC644450 uncharacterized LOC644450
LTBP4 latent transforming growth factor beta binding protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MARS methionyl-tRNA synthetase
MFAP3L microfibrillar-associated protein 3-like
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL3 male-specific lethal 3 homolog (Drosophila)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
NAV2 neuron navigator 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPR1 natriuretic peptide receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PCBP3 poly(rC) binding protein 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RGS2 regulator of G-protein signaling 2
RPL10 ribosomal protein L10
RUNX1 runt-related transcription factor 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SYBU syntabulin (syntaxin-interacting)
TAZ tafazzin
TDRD1 tudor domain containing 1
TIMP3 TIMP metallopeptidase inhibitor 3
TJAP1 tight junction associated protein 1 (peripheral)
TMED7 transmembrane emp24 protein transport domain containing 7
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRABD TraB domain containing
TTLL1 tubulin tyrosine ligase-like family member 1
UBA6 ubiquitin-like modifier activating enzyme 6
VEGFA vascular endothelial growth factor A
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
AES amino-terminal enhancer of split
ARC activity-regulated cytoskeleton-associated protein
ARSB arylsulfatase B
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1ORF35 chromosome 1 open reading frame 35
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CDR2L cerebellar degeneration-related protein 2-like
CEP70 centrosomal protein 70kDa
CFAP44 cilia and flagella associated protein 44
CNGB3 cyclic nucleotide gated channel beta 3
CTSF cathepsin F
CXORF56 chromosome X open reading frame 56
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFHD1 EF-hand domain family, member D1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155B family with sequence similarity 155, member B
FBXO31 F-box protein 31
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
FMOD fibromodulin
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLI3 GLI family zinc finger 3
GRPR gastrin-releasing peptide receptor
GRTP1 growth hormone regulated TBC protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HS1BP3 HCLS1 binding protein 3
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM7A lysine (K)-specific demethylase 7A
KLHL26 kelch-like family member 26
LAMB3 laminin, beta 3
LOC257152 uncharacterized LOC257152
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST3 microtubule associated serine/threonine kinase 3
MCOLN3 mucolipin 3
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARPBP PARP1 binding protein
PCDHB3 protocadherin beta 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POLH polymerase (DNA directed), eta
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
RAD54L RAD54-like (S. cerevisiae)
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPH3AL rabphilin 3A-like (without C2 domains)
SCD5 stearoyl-CoA desaturase 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SECISBP2 SECIS binding protein 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD1A SET domain containing 1A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SNORA21 small nucleolar RNA, H/ACA box 21
SPINK5 serine peptidase inhibitor, Kazal type 5
ST5 suppression of tumorigenicity 5
STAG3 stromal antigen 3
SULT4A1 sulfotransferase family 4A, member 1
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TEAD3 TEA domain family member 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TPCN1 two pore segment channel 1
TRAF5 TNF receptor-associated factor 5
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UPP1 uridine phosphorylase 1
USP20 ubiquitin specific peptidase 20
WNT10B wingless-type MMTV integration site family, member 10B
ZDHHC18 zinc finger, DHHC-type containing 18
ZMYM3 zinc finger, MYM-type 3
ZNF134 zinc finger protein 134
ZNF248 zinc finger protein 248
ZNF276 zinc finger protein 276
ZNF480 zinc finger protein 480
ZNF484 zinc finger protein 484
ZNF586 zinc finger protein 586
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76