| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the lynestrenol-1953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACAN | aggrecan |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD40 | ankyrin repeat domain 40 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF3 | activating transcription factor 3 |
| ATXN7L3B | ataxin 7-like 3B |
| AVEN | apoptosis, caspase activation inhibitor |
| AVPR1B | arginine vasopressin receptor 1B |
| BCL2A1 | BCL2-related protein A1 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BMP2K | BMP2 inducible kinase |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CD24 | CD24 molecule |
| CDC27 | cell division cycle 27 |
| CDC45 | cell division cycle 45 |
| CES2 | carboxylesterase 2 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CPT2 | carnitine palmitoyltransferase 2 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DENND3 | DENN/MADD domain containing 3 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| EMP1 | epithelial membrane protein 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FNBP1 | formin binding protein 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLE1 | GLE1 RNA export mediator |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| H2AFY2 | H2A histone family, member Y2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMOX1 | heme oxygenase 1 |
| HOXB5 | homeobox B5 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL6 | interleukin 6 |
| KLF12 | Kruppel-like factor 12 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LITAF | lipopolysaccharide-induced TNF factor |
| LRRC49 | leucine rich repeat containing 49 |
| MAL | mal, T-cell differentiation protein |
| MAOA | monoamine oxidase A |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MECP2 | methyl CpG binding protein 2 |
| MED16 | mediator complex subunit 16 |
| METTL22 | methyltransferase like 22 |
| MICALL1 | MICAL-like 1 |
| MSH3 | mutS homolog 3 |
| NAAA | N-acylethanolamine acid amidase |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NIPAL3 | NIPA-like domain containing 3 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NOTCH2 | notch 2 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| OSBPL2 | oxysterol binding protein-like 2 |
| PC | pyruvate carboxylase |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKCD | protein kinase C, delta |
| PRPF4B | pre-mRNA processing factor 4B |
| PRRC2B | proline-rich coiled-coil 2B |
| RHOC | ras homolog family member C |
| RPE | ribulose-5-phosphate-3-epimerase |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STC1 | stanniocalcin 1 |
| SURF2 | surfeit 2 |
| TBL1X | transducin (beta)-like 1X-linked |
| TFCP2 | transcription factor CP2 |
| THADA | thyroid adenoma associated |
| TMEM104 | transmembrane protein 104 |
| TMEM161A | transmembrane protein 161A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 |
| TRIM29 | tripartite motif containing 29 |
| TUB | tubby bipartite transcription factor |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| USP20 | ubiquitin specific peptidase 20 |
| VAMP3 | vesicle-associated membrane protein 3 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WTAP | Wilms tumor 1 associated protein |
| ZNF318 | zinc finger protein 318 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACVR2B | activin A receptor, type IIB |
| ACYP2 | acylphosphatase 2, muscle type |
| AMOTL2 | angiomotin like 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CASZ1 | castor zinc finger 1 |
| CD53 | CD53 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN2AIP | CDKN2A interacting protein |
| CEP170B | centrosomal protein 170B |
| CEP70 | centrosomal protein 70kDa |
| CEP97 | centrosomal protein 97kDa |
| CFD | complement factor D (adipsin) |
| CISH | cytokine inducible SH2-containing protein |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CROT | carnitine O-octanoyltransferase |
| CTSF | cathepsin F |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCTN4 | dynactin 4 (p62) |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DENND1B | DENN/MADD domain containing 1B |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DPYD | dihydropyrimidine dehydrogenase |
| DRD5 | dopamine receptor D5 |
| EFNA4 | ephrin-A4 |
| EMC2 | ER membrane protein complex subunit 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM169A | family with sequence similarity 169, member A |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| FAM53B | family with sequence similarity 53, member B |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXO46 | F-box protein 46 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GCA | grancalcin, EF-hand calcium binding protein |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLX | H2.0-like homeobox |
| IFI6 | interferon, alpha-inducible protein 6 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIF20B | kinesin family member 20B |
| LHFP | lipoma HMGIC fusion partner |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAGEA3 | melanoma antigen family A3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| METTL1 | methyltransferase like 1 |
| METTL8 | methyltransferase like 8 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGA | MGA, MAX dimerization protein |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| NBEA | neurobeachin |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RNF220 | ring finger protein 220 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SACS | sacsin molecular chaperone |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D10B | TBC1 domain family, member 10B |
| THAP7 | THAP domain containing 7 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM68 | tripartite motif containing 68 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBP1 | upstream binding protein 1 (LBP-1a) |
| UFM1 | ubiquitin-fold modifier 1 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF189 | zinc finger protein 189 |
| ZNF623 | zinc finger protein 623 |
| ZNF654 | zinc finger protein 654 |