lynestrenol-5355 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the lynestrenol-5355 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
AKR1C2 aldo-keto reductase family 1, member C2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARTN artemin
ATF3 activating transcription factor 3
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BST2 bone marrow stromal cell antigen 2
C10ORF95 chromosome 10 open reading frame 95
CACTIN cactin, spliceosome C complex subunit
CD22 CD22 molecule
CD52 CD52 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CRAT carnitine O-acetyltransferase
CTAGE5 CTAGE family, member 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
E2F4 E2F transcription factor 4, p107/p130-binding
EGR1 early growth response 1
GATA4 GATA binding protein 4
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOLGA2 golgin A2
HIST1H2BO histone cluster 1, H2bo
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HNF1B HNF1 homeobox B
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
INHBE inhibin, beta E
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IPO5 importin 5
IRF1 interferon regulatory factor 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNIP1 Kv channel interacting protein 1
LAMA3 laminin, alpha 3
LAT2 linker for activation of T cells family, member 2
LIME1 Lck interacting transmembrane adaptor 1
LOC647070 uncharacterized LOC647070
LONP2 lon peptidase 2, peroxisomal
LRRC41 leucine rich repeat containing 41
LRRC61 leucine rich repeat containing 61
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK11 mitogen-activated protein kinase 11
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYOF myoferlin
NKX3-2 NK3 homeobox 2
NPTX1 neuronal pentraxin I
NR1H2 nuclear receptor subfamily 1, group H, member 2
NXPH4 neurexophilin 4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCG1 phospholipase C, gamma 1
POPDC3 popeye domain containing 3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RBBP9 retinoblastoma binding protein 9
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RPL35A ribosomal protein L35a
S100A9 S100 calcium binding protein A9
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFXN3 sideroflexin 3
SH3BP2 SH3-domain binding protein 2
SIK1 salt-inducible kinase 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOCS1 suppressor of cytokine signaling 1
SOX12 SRY (sex determining region Y)-box 12
SOX9 SRY (sex determining region Y)-box 9
SPX spexin hormone
STK17A serine/threonine kinase 17a
SYBU syntabulin (syntaxin-interacting)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCF3 transcription factor 3
TFF2 trefoil factor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM2 tripartite motif containing 2
TSKU tsukushi, small leucine rich proteoglycan
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL5 tubulin tyrosine ligase-like family member 5
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZC3H3 zinc finger CCCH-type containing 3
ZNF224 zinc finger protein 224
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTN4 actinin, alpha 4
AHDC1 AT hook, DNA binding motif, containing 1
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD36 ankyrin repeat domain 36
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAHD1 bromo adjacent homology domain containing 1
BBS7 Bardet-Biedl syndrome 7
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C4ORF29 chromosome 4 open reading frame 29
CBX4 chromobox homolog 4
CLDN15 claudin 15
COCH cochlin
COL4A5 collagen, type IV, alpha 5
CORO1A coronin, actin binding protein, 1A
CRYL1 crystallin, lambda 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS11 dehydrogenase/reductase (SDR family) member 11
DVL1 dishevelled segment polarity protein 1
EDC3 enhancer of mRNA decapping 3
ERCC3 excision repair cross-complementation group 3
GAA glucosidase, alpha; acid
GAS8 growth arrest-specific 8
GBAS glioblastoma amplified sequence
GHR growth hormone receptor
GSTM2 glutathione S-transferase mu 2 (muscle)
HMGB3 high mobility group box 3
HS1BP3 HCLS1 binding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KIAA0894 KIAA0894 protein
LMNB1 lamin B1
LYPD1 LY6/PLAUR domain containing 1
MCRS1 microspherule protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MEIS2 Meis homeobox 2
METTL8 methyltransferase like 8
MICALL2 MICAL-like 2
MPI mannose phosphate isomerase
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPH non-SMC condensin I complex, subunit H
NPFFR1 neuropeptide FF receptor 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NPY5R neuropeptide Y receptor Y5
ORAI3 ORAI calcium release-activated calcium modulator 3
OXTR oxytocin receptor
PCBP4 poly(rC) binding protein 4
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCTP phosphatidylcholine transfer protein
PLA2G12A phospholipase A2, group XIIA
PLD3 phospholipase D family, member 3
PMP22 peripheral myelin protein 22
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTDSS2 phosphatidylserine synthase 2
PTGES2 prostaglandin E synthase 2
PTK6 protein tyrosine kinase 6
RHOC ras homolog family member C
RINT1 RAD50 interactor 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RSF1 remodeling and spacing factor 1
RUFY2 RUN and FYVE domain containing 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SF3B2 splicing factor 3b, subunit 2, 145kDa
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3BGR SH3 domain binding glutamate-rich protein
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNX6 sorting nexin 6
STK16 serine/threonine kinase 16
TESK2 testis-specific kinase 2
TK1 thymidine kinase 1, soluble
TMEM38B transmembrane protein 38B
TPCN1 two pore segment channel 1
TRIM45 tripartite motif containing 45
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC26 tetratricopeptide repeat domain 26
TTF2 transcription termination factor, RNA polymerase II
USP6NL USP6 N-terminal like
WDR82 WD repeat domain 82
WWC2 WW and C2 domain containing 2
YIPF3 Yip1 domain family, member 3
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZMAT5 zinc finger, matrin-type 5
ZMYM1 zinc finger, MYM-type 1
ZNF273 zinc finger protein 273
ZNF480 zinc finger protein 480