lysergol-1325 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lysergol-1325 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AK1 adenylate kinase 1
AKAP8L A kinase (PRKA) anchor protein 8-like
APOL2 apolipoprotein L, 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP11A ATPase, class VI, type 11A
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BAK1 BCL2-antagonist/killer 1
BEST1 bestrophin 1
BICD1 bicaudal D homolog 1 (Drosophila)
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDCP1 CUB domain containing protein 1
CLTA clathrin, light chain A
CORT cortistatin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1C DENN/MADD domain containing 1C
DLG4 discs, large homolog 4 (Drosophila)
DNMBP dynamin binding protein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FLJ42627 uncharacterized LOC645644
FUZ fuzzy planar cell polarity protein
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GCAT glycine C-acetyltransferase
GPSM3 G-protein signaling modulator 3
GPX2 glutathione peroxidase 2
GRIP2 glutamate receptor interacting protein 2
GSDMD gasdermin D
HTATSF1 HIV-1 Tat specific factor 1
ICAM1 intercellular adhesion molecule 1
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INPP5K inositol polyphosphate-5-phosphatase K
ITSN1 intersectin 1 (SH3 domain protein)
KAZN kazrin, periplakin interacting protein
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLHL12 kelch-like family member 12
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC730101 uncharacterized LOC730101
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MZT2B mitotic spindle organizing protein 2B
NCALD neurocalcin delta
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PACS2 phosphofurin acidic cluster sorting protein 2
PLXNA1 plexin A1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRAF2 PRA1 domain family, member 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PSD3 pleckstrin and Sec7 domain containing 3
PYGB phosphorylase, glycogen; brain
RABGAP1L RAB GTPase activating protein 1-like
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REEP1 receptor accessory protein 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUNX1 runt-related transcription factor 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2D4A SH2 domain containing 4A
SHOX2 short stature homeobox 2
SIRT5 sirtuin 5
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRR serine racemase
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STXBP6 syntaxin binding protein 6 (amisyn)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBX6 T-box 6
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THBS4 thrombospondin 4
TMC6 transmembrane channel-like 6
TRIM3 tripartite motif containing 3
TRMT61A tRNA methyltransferase 61A
TYMS thymidylate synthetase
UBXN1 UBX domain protein 1
USP18 ubiquitin specific peptidase 18
USP22 ubiquitin specific peptidase 22
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
WNT16 wingless-type MMTV integration site family, member 16
XAB2 XPA binding protein 2
ZNF79 zinc finger protein 79
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADAP2 ArfGAP with dual PH domains 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASB6 ankyrin repeat and SOCS box containing 6
BCL2L2 BCL2-like 2
BTBD18 BTB (POZ) domain containing 18
C1ORF123 chromosome 1 open reading frame 123
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CCDC25 coiled-coil domain containing 25
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CECR1 cat eye syndrome chromosome region, candidate 1
CEP70 centrosomal protein 70kDa
COL9A2 collagen, type IX, alpha 2
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR2 early growth response 2
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHB6 EPH receptor B6
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD2 exonuclease 3'-5' domain containing 2
EXOC2 exocyst complex component 2
F8 coagulation factor VIII, procoagulant component
FAM173A family with sequence similarity 173, member A
FAM57A family with sequence similarity 57, member A
FAM63A family with sequence similarity 63, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCHO1 FCH domain only 1
FLCN folliculin
FZD2 frizzled class receptor 2
GCH1 GTP cyclohydrolase 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOOK2 hook microtubule-tethering protein 2
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IRX5 iroquois homeobox 5
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0232 KIAA0232
KLHDC4 kelch domain containing 4
LIG4 ligase IV, DNA, ATP-dependent
LRRK1 leucine-rich repeat kinase 1
MBTD1 mbt domain containing 1
METTL22 methyltransferase like 22
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICALL2 MICAL-like 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOL12 nucleolar protein 12
NPDC1 neural proliferation, differentiation and control, 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARG poly (ADP-ribose) glycohydrolase
PARPBP PARP1 binding protein
PEX1 peroxisomal biogenesis factor 1
PLA2G15 phospholipase A2, group XV
POLM polymerase (DNA directed), mu
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTCD1 pentatricopeptide repeat domain 1
QPRT quinolinate phosphoribosyltransferase
RABEPK Rab9 effector protein with kelch motifs
RFTN1 raftlin, lipid raft linker 1
RFX7 regulatory factor X, 7
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL39L ribosomal protein L39-like
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMD9 sterile alpha motif domain containing 9
SGMS1 sphingomyelin synthase 1
SHPK sedoheptulokinase
SIDT1 SID1 transmembrane family, member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNRPC small nuclear ribonucleoprotein polypeptide C
SPA17 sperm autoantigenic protein 17
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM134 transmembrane protein 134
TMEM209 transmembrane protein 209
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM25 tripartite motif containing 25
TXLNG taxilin gamma
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBQLN4 ubiquilin 4
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XPO4 exportin 4
ZNF141 zinc finger protein 141
ZNF223 zinc finger protein 223
ZNF747 zinc finger protein 747