lysergol-3261 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lysergol-3261 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AHNAK2 AHNAK nucleoprotein 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKLE2 ankyrin repeat and LEM domain containing 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATRNL1 attractin-like 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BMP5 bone morphogenetic protein 5
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C21ORF2 chromosome 21 open reading frame 2
C3AR1 complement component 3a receptor 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCPG1 cell cycle progression 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFLAR CASP8 and FADD-like apoptosis regulator
CNTFR ciliary neurotrophic factor receptor
CPNE7 copine VII
CTBP2 C-terminal binding protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DMPK dystrophia myotonica-protein kinase
DMTN dematin actin binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSC2 desmocollin 2
DUSP13 dual specificity phosphatase 13
EFR3B EFR3 homolog B (S. cerevisiae)
F5 coagulation factor V (proaccelerin, labile factor)
FCAR Fc fragment of IgA receptor
FGF2 fibroblast growth factor 2 (basic)
FLT4 fms-related tyrosine kinase 4
FSCN1 fascin actin-bundling protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK glycerol kinase
GLB1L galactosidase, beta 1-like
GLS glutaminase
GPR143 G protein-coupled receptor 143
HOXA4 homeobox A4
HPS1 Hermansky-Pudlak syndrome 1
IGFBP5 insulin-like growth factor binding protein 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB5 integrin, beta 5
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA1456 KIAA1456
KLHL20 kelch-like family member 20
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LEFTY2 left-right determination factor 2
LRRC23 leucine rich repeat containing 23
MET MET proto-oncogene, receptor tyrosine kinase
MID1 midline 1
MOCS3 molybdenum cofactor synthesis 3
MTM1 myotubularin 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NNAT neuronatin
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUMA1 nuclear mitotic apparatus protein 1
NUP88 nucleoporin 88kDa
OGG1 8-oxoguanine DNA glycosylase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYHIN1 pyrin and HIN domain family, member 1
RAD51D RAD51 paralog D
RIN2 Ras and Rab interactor 2
RPL35A ribosomal protein L35a
RUFY3 RUN and FYVE domain containing 3
SCAF4 SR-related CTD-associated factor 4
SCAND2P SCAN domain containing 2 pseudogene
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMC4 structural maintenance of chromosomes 4
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPG20 spastic paraplegia 20 (Troyer syndrome)
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TOP3A topoisomerase (DNA) III alpha
TSC22D2 TSC22 domain family, member 2
TWF2 twinfilin actin binding protein 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZDHHC11 zinc finger, DHHC-type containing 11
ZFHX2 zinc finger homeobox 2
ZFHX4 zinc finger homeobox 4
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACTL8 actin-like 8
ACYP2 acylphosphatase 2, muscle type
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADRA2C adrenoceptor alpha 2C
ALS2CL ALS2 C-terminal like
APLP1 amyloid beta (A4) precursor-like protein 1
APOO apolipoprotein O
AXIN1 axin 1
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
CA5BP1 carbonic anhydrase VB pseudogene 1
CABIN1 calcineurin binding protein 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CDK3 cyclin-dependent kinase 3
CLASRP CLK4-associating serine/arginine rich protein
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
DEAF1 DEAF1 transcription factor
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHD3 EH-domain containing 3
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FADS2 fatty acid desaturase 2
FAM131A family with sequence similarity 131, member A
FAM184A family with sequence similarity 184, member A
FICD FIC domain containing
GADD45G growth arrest and DNA-damage-inducible, gamma
GCA grancalcin, EF-hand calcium binding protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H4F histone cluster 1, H4f
HOXC13 homeobox C13
HYI hydroxypyruvate isomerase (putative)
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KIAA0319L KIAA0319-like
KIFC1 kinesin family member C1
KLK5 kallikrein-related peptidase 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC61 leucine rich repeat containing 61
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX1 neuronal pentraxin I
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
OVOL1 ovo-like zinc finger 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
PRAMEF11 PRAME family member 11
PTGES2 prostaglandin E synthase 2
RAB5B RAB5B, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RBM15B RNA binding motif protein 15B
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD1A SET domain containing 1A
SIX1 SIX homeobox 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SRPX sushi-repeat containing protein, X-linked
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TKFC triokinase/FMN cyclase
USP20 ubiquitin specific peptidase 20
VEGFC vascular endothelial growth factor C
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF276 zinc finger protein 276
ZNF282 zinc finger protein 282
ZNF350 zinc finger protein 350
ZNF778 zinc finger protein 778