lysergol-4966 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the lysergol-4966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
AIF1 allograft inflammatory factor 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARFRP1 ADP-ribosylation factor related protein 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC85C coiled-coil domain containing 85C
CCKAR cholecystokinin A receptor
CD1C CD1c molecule
CD22 CD22 molecule
CD58 CD58 molecule
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CSF1 colony stimulating factor 1 (macrophage)
CST4 cystatin S
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DIXDC1 DIX domain containing 1
DMPK dystrophia myotonica-protein kinase
DMTN dematin actin binding protein
DNASE1L3 deoxyribonuclease I-like 3
EDA ectodysplasin A
EGFR epidermal growth factor receptor
EMP3 epithelial membrane protein 3
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
EXOSC1 exosome component 1
FAM131A family with sequence similarity 131, member A
FAM134B family with sequence similarity 134, member B
FOXA2 forkhead box A2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRY furry homolog (Drosophila)
GPC3 glypican 3
GSTA4 glutathione S-transferase alpha 4
GSTP1 glutathione S-transferase pi 1
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IDS iduronate 2-sulfatase
IFNA14 interferon, alpha 14
INHBA inhibin, beta A
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF4 interferon regulatory factor 4
IRS2 insulin receptor substrate 2
ITGA7 integrin, alpha 7
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLF12 Kruppel-like factor 12
KRTAP9-9 keratin associated protein 9-9
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRP6 low density lipoprotein receptor-related protein 6
LTBP2 latent transforming growth factor beta binding protein 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEF2D myocyte enhancer factor 2D
MKL1 megakaryoblastic leukemia (translocation) 1
MST1L macrophage stimulating 1-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAPH2 non-SMC condensin II complex, subunit H2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NDRG2 NDRG family member 2
NMT1 N-myristoyltransferase 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
PCDHGB5 protocadherin gamma subfamily B, 5
PIDD1 p53-induced death domain protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POPDC3 popeye domain containing 3
PROL1 proline rich, lacrimal 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTRF polymerase I and transcript release factor
RBM5 RNA binding motif protein 5
REC8 REC8 meiotic recombination protein
RPL35A ribosomal protein L35a
RTCA RNA 3'-terminal phosphate cyclase
SAA3P serum amyloid A3 pseudogene
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERGEF secretion regulating guanine nucleotide exchange factor
SETBP1 SET binding protein 1
SIDT2 SID1 transmembrane family, member 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD3 SMAD family member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SSTR5 somatostatin receptor 5
SSX3 synovial sarcoma, X breakpoint 3
TAT tyrosine aminotransferase
THOC5 THO complex 5
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM19 transmembrane protein 19
TMEM63A transmembrane protein 63A
TNNT2 troponin T type 2 (cardiac)
TPMT thiopurine S-methyltransferase
UNC119 unc-119 homolog (C. elegans)
WIZ widely interspaced zinc finger motifs
WT1 Wilms tumor 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOT8 acyl-CoA thioesterase 8
ACTL8 actin-like 8
ACTN4 actinin, alpha 4
ADCK3 aarF domain containing kinase 3
ADGRE5 adhesion G protein-coupled receptor E5
AMT aminomethyltransferase
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD2B ATPase family, AAA domain containing 2B
ATF3 activating transcription factor 3
BAG4 BCL2-associated athanogene 4
BCL9 B-cell CLL/lymphoma 9
C11ORF80 chromosome 11 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C1ORF115 chromosome 1 open reading frame 115
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC121 coiled-coil domain containing 121
CCDC132 coiled-coil domain containing 132
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CIC capicua transcriptional repressor
CLDN15 claudin 15
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COG4 component of oligomeric golgi complex 4
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
EFHD2 EF-hand domain family, member D2
ETAA1 Ewing tumor-associated antigen 1
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FKBP5 FK506 binding protein 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALK1 galactokinase 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA4 GATA binding protein 4
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLB1L2 galactosidase, beta 1-like 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC4 histone deacetylase 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HMHA1 histocompatibility (minor) HA-1
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT81 intraflagellar transport 81
IMPACT impact RWD domain protein
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
LPXN leupaxin
MANBA mannosidase, beta A, lysosomal
METTL16 methyltransferase like 16
MRPL52 mitochondrial ribosomal protein L52
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NECAP2 NECAP endocytosis associated 2
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRGN neurogranin (protein kinase C substrate, RC3)
PAQR3 progestin and adipoQ receptor family member III
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX26 peroxisomal biogenesis factor 26
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G12A phospholipase A2, group XIIA
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RCOR3 REST corepressor 3
RLN1 relaxin 1
SH2D4A SH2 domain containing 4A
SHARPIN SHANK-associated RH domain interactor
SLC12A8 solute carrier family 12, member 8
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOWAHC sosondowah ankyrin repeat domain family member C
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TESC tescalcin
TRAIP TRAF interacting protein
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF226 zinc finger protein 226
ZNF286A zinc finger protein 286A
ZNF318 zinc finger protein 318
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770