lysergol-6621 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the lysergol-6621 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADGRE3 adhesion G protein-coupled receptor E3
AGTR1 angiotensin II receptor, type 1
BAAT bile acid CoA:amino acid N-acyltransferase
C19ORF66 chromosome 19 open reading frame 66
C8A complement component 8, alpha polypeptide
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALHM2 calcium homeostasis modulator 2
CCR9 chemokine (C-C motif) receptor 9
CD177 CD177 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP164 centrosomal protein 164kDa
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CSF1R colony stimulating factor 1 receptor
CST4 cystatin S
DUSP10 dual specificity phosphatase 10
EDN3 endothelin 3
EMID1 EMI domain containing 1
ESRRG estrogen-related receptor gamma
FABP2 fatty acid binding protein 2, intestinal
FBLN1 fibulin 1
FGF5 fibroblast growth factor 5
FLRT1 fibronectin leucine rich transmembrane protein 1
FLT1 fms-related tyrosine kinase 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXO4 forkhead box O4
GIMAP5 GTPase, IMAP family member 5
GSN gelsolin
GSTTP1 glutathione S-transferase theta pseudogene 1
GTDC1 glycosyltransferase-like domain containing 1
HOXD10 homeobox D10
HSPA12A heat shock 70kDa protein 12A
HSPB6 heat shock protein, alpha-crystallin-related, B6
IDS iduronate 2-sulfatase
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM1 interferon induced transmembrane protein 1
IL5RA interleukin 5 receptor, alpha
JUND jun D proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1109 KIAA1109
KIF21B kinesin family member 21B
KRT14 keratin 14, type I
LAMA2 laminin, alpha 2
LINC00472 long intergenic non-protein coding RNA 472
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MXRA5 matrix-remodelling associated 5
NCAM1 neural cell adhesion molecule 1
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPY neuropeptide Y
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLXDC1 plexin domain containing 1
PML promyelocytic leukemia
POU4F1 POU class 4 homeobox 1
PRPF18 pre-mRNA processing factor 18
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB36 RAB36, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RNF122 ring finger protein 122
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RRAGD Ras-related GTP binding D
RSAD2 radical S-adenosyl methionine domain containing 2
RUNDC3A RUN domain containing 3A
SCN5A sodium channel, voltage gated, type V alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SP110 SP110 nuclear body protein
SPTB spectrin, beta, erythrocytic
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK16 serine/threonine kinase 16
STS steroid sulfatase (microsomal), isozyme S
SYT5 synaptotagmin V
TCF3 transcription factor 3
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP3 TIMP metallopeptidase inhibitor 3
TLE4 transducin-like enhancer of split 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNRC6B trinucleotide repeat containing 6B
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM22 tripartite motif containing 22
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZHX3 zinc fingers and homeoboxes 3

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AKIP1 A kinase (PRKA) interacting protein 1
ALPK1 alpha-kinase 1
ANGPTL4 angiopoietin-like 4
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C11ORF80 chromosome 11 open reading frame 80
C4ORF29 chromosome 4 open reading frame 29
C5ORF42 chromosome 5 open reading frame 42
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC94 coiled-coil domain containing 94
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CDT1 chromatin licensing and DNA replication factor 1
CLDN1 claudin 1
CLDN14 claudin 14
CLDN15 claudin 15
CLSPN claspin
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ELP6 elongator acetyltransferase complex subunit 6
EPHA4 EPH receptor A4
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FURIN furin (paired basic amino acid cleaving enzyme)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTPBP6 GTP binding protein 6 (putative)
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HLA-DMA major histocompatibility complex, class II, DM alpha
HLX H2.0-like homeobox
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITPKC inositol-trisphosphate 3-kinase C
JUNB jun B proto-oncogene
KIAA0319L KIAA0319-like
KLHL36 kelch-like family member 36
KRT8P12 keratin 8 pseudogene 12
LAMC3 laminin, gamma 3
LRRC37A3 leucine rich repeat containing 37, member A3
LSR lipolysis stimulated lipoprotein receptor
LY96 lymphocyte antigen 96
LYPD3 LY6/PLAUR domain containing 3
MED9 mediator complex subunit 9
MTA2 metastasis associated 1 family, member 2
MTERF4 mitochondrial transcription termination factor 4
MTMR6 myotubularin related protein 6
MXRA8 matrix-remodelling associated 8
MYLIP myosin regulatory light chain interacting protein
NINL ninein-like
NME5 NME/NM23 family member 5
NR2C2 nuclear receptor subfamily 2, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPT2 palmitoyl-protein thioesterase 2
PRF1 perforin 1 (pore forming protein)
PRICKLE3 prickle homolog 3 (Drosophila)
PTK6 protein tyrosine kinase 6
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SH3GL2 SH3-domain GRB2-like 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG20 small nucleolar RNA host gene 20
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TGFB3 transforming growth factor, beta 3
THBS3 thrombospondin 3
TMEM184B transmembrane protein 184B
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
WDR76 WD repeat domain 76
WFDC2 WAP four-disulfide core domain 2
YPEL1 yippee-like 1 (Drosophila)
ZNF214 zinc finger protein 214
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652