mac Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. (Gene Ontology, GO_0005579)
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Genes

8 genes co-occuring with the biological term mac in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
C6 complement component 6
C8A complement component 8, alpha polypeptide
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
VEGFA vascular endothelial growth factor A