machado-joseph disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A spinocerebellar ataxia that is characterized by slow degeneration of the hindbrain and has_material_basis_in expansion of CAG triplet repeats (glutamine) in the ATXN3 gene. (Human Disease Ontology, DOID_1440)
Similar Terms
Downloads & Tools

Genes

75 genes co-occuring with the disease machado-joseph disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ATXN3 ataxin 3 3.94843
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 1.70679
SPTBN2 spectrin, beta, non-erythrocytic 2 1.6368
C10ORF2 chromosome 10 open reading frame 2 1.47506
JOSD2 Josephin domain containing 2 1.38559
VCP valosin containing protein 1.28566
ATXN3L ataxin 3-like 1.2508
JOSD1 Josephin domain containing 1 1.23429
ATXN7 ataxin 7 1.15368
CA11 carbonic anhydrase XI 1.13374
PDYN prodynorphin 1.08118
RAD23A RAD23 homolog A (S. cerevisiae) 1.08034
MARCH5 membrane-associated ring finger (C3HC4) 5 1.03114
RAD23B RAD23 homolog B (S. cerevisiae) 0.984321
ATXN2 ataxin 2 0.961216
RPA3 replication protein A3, 14kDa 0.892948
ATN1 atrophin 1 0.892538
AR androgen receptor 0.863046
HTT huntingtin 0.817976
PARK2 parkin RBR E3 ubiquitin protein ligase 0.765535
SRSF9 serine/arginine-rich splicing factor 9 0.709572
NBR1 neighbor of BRCA1 gene 1 0.690293
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.680697
SNX9 sorting nexin 9 0.656046
FGF14 fibroblast growth factor 14 0.630813
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.622575
TTBK2 tau tubulin kinase 2 0.617486
ATXN1 ataxin 1 0.607323
BECN1 beclin 1, autophagy related 0.604201
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.588612
ZFYVE26 zinc finger, FYVE domain containing 26 0.578883
MRO maestro 0.577716
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.571107
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.564112
TIMELESS timeless circadian clock 0.526132
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.511112
RAI1 retinoic acid induced 1 0.500761
AFF2 AF4/FMR2 family, member 2 0.49274
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.49274
TBP TATA box binding protein 0.467306
BEAN1 brain expressed, associated with NEDD4, 1 0.43941
MIR25 microRNA 25 0.422515
PANK1 pantothenate kinase 1 0.416521
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.388909
SPG11 spastic paraplegia 11 (autosomal recessive) 0.382594
CAST calpastatin 0.365932
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.365932
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.357446
DCX doublecortin 0.346042
CUL1 cullin 1 0.33066
CD3D CD3d molecule, delta (CD3-TCR complex) 0.32373
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.319726
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.307033
CLOCK clock circadian regulator 0.301615
CALB1 calbindin 1, 28kDa 0.293694
FXN frataxin 0.280796
SEPT5 septin 5 0.279011
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.275089
S100B S100 calcium binding protein B 0.275089
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.271174
PANK2 pantothenate kinase 2 0.258417
CDK7 cyclin-dependent kinase 7 0.239101
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.222822
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.208245
HSPA4 heat shock 70kDa protein 4 0.205585
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.196459
XPO1 exportin 1 0.185016
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.18472
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.177576
UBE2S ubiquitin-conjugating enzyme E2S 0.176757
PGM1 phosphoglucomutase 1 0.170299
ADORA2A adenosine A2a receptor 0.170299
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.169091
ATG7 autophagy related 7 0.168617
CA8 carbonic anhydrase VIII 0.159124