macrophage activation involved in immune response Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. (Gene Ontology, GO_0002281)
External Link http://amigo.geneontology.org/amigo/term/GO:0002281
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Genes

12 genes participating in the macrophage activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
CX3CR1 chemokine (C-X3-C motif) receptor 1
DYSF dysferlin
GRN granulin
IFI35 interferon-induced protein 35
IFNG interferon, gamma
LBP lipopolysaccharide binding protein
NMI N-myc (and STAT) interactor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
SBNO2 strawberry notch homolog 2 (Drosophila)
SYK spleen tyrosine kinase
TREM2 triggering receptor expressed on myeloid cells 2
TYROBP TYRO protein tyrosine kinase binding protein