macrophage differentiation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. (Gene Ontology, GO_0030225)
External Link http://amigo.geneontology.org/amigo/term/GO:0030225
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Genes

25 genes participating in the macrophage differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ARID3C AT rich interactive domain 3C (BRIGHT-like)
BMP4 bone morphogenetic protein 4
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD4 CD4 molecule
CDC42 cell division cycle 42
CFLAR CASP8 and FADD-like apoptosis regulator
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
GATA3 GATA binding protein 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
IL15 interleukin 15
IL31RA interleukin 31 receptor A
IL33 interleukin 33
IL33R interleukin 33 receptor
LIF leukemia inhibitory factor
MMP9 matrix metallopeptidase 9
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PARP1 poly (ADP-ribose) polymerase 1
QKI QKI, KH domain containing, RNA binding
SIRT1 sirtuin 1
SOCS1 suppressor of cytokine signaling 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A