macrophage Gene Set

Dataset TISSUES Curated Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kupffer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans giant cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000801)
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Genes

43 proteins highly expressed in the tissue macrophage from the TISSUES Curated Tissue Protein Expression Evidence Scores dataset.

Symbol Name
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ACP5 acid phosphatase 5, tartrate resistant
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
C15ORF48 chromosome 15 open reading frame 48
CCL22 chemokine (C-C motif) ligand 22
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CES1 carboxylesterase 1
CHIT1 chitinase 1 (chitotriosidase)
CLEC4D C-type lectin domain family 4, member D
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CTSK cathepsin K
CTSS cathepsin S
EMILIN2 elastin microfibril interfacer 2
FCAR Fc fragment of IgA receptor
FUOM fucose mutarotase
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
HBEGF heparin-binding EGF-like growth factor
IL36B interleukin 36, beta
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JOSD2 Josephin domain containing 2
M1AP meiosis 1 associated protein
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MMP12 matrix metallopeptidase 12
OSCAR osteoclast associated, immunoglobulin-like receptor
PQLC2 PQ loop repeat containing 2
RPL26 ribosomal protein L26
SIGLEC14 sialic acid binding Ig-like lectin 14
SLAMF7 SLAM family member 7
SOAT1 sterol O-acyltransferase 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TLR5 toll-like receptor 5
TM4SF19 transmembrane 4 L six family member 19
TMEM176B transmembrane protein 176B
TYROBP TYRO protein tyrosine kinase binding protein
VMO1 vitelline membrane outer layer 1 homolog (chicken)