macropinocytic cup Gene Set

Dataset	COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category	structural or functional annotations
Type	cellular component
Description	A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin. (Gene Ontology, GO_0070685)
Similar Terms
Downloads & Tools

Genes

18 proteins co-occuring with the macropinocytic cup cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol	Name	Standardized Value
RAB21	RAB21, member RAS oncogene family	1.41418
SNX18	sorting nexin 18	1.28623
RAB20	RAB20, member RAS oncogene family	1.24027
SNX33	sorting nexin 33	1.23713
SNX5	sorting nexin 5	0.950665
PLCD1	phospholipase C, delta 1	0.874107
SNX9	sorting nexin 9	0.852961
CTBP1	C-terminal binding protein 1	0.759978
SNX1	sorting nexin 1	0.687264
PLEK	pleckstrin	0.609086
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.582594
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.580922
ANXA7	annexin A7	0.523476
SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	0.499853
BTK	Bruton agammaglobulinemia tyrosine kinase	0.481661
EEA1	early endosome antigen 1	0.336619
PTEN	phosphatase and tensin homolog	0.198658
LAMP1	lysosomal-associated membrane protein 1	0.198325