| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mafenide-1441 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATXN7 | ataxin 7 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BRCA2 | breast cancer 2, early onset |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C5AR1 | complement component 5a receptor 1 |
| CBX6 | chromobox homolog 6 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTSS | cathepsin S |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ELMO2 | engulfment and cell motility 2 |
| EPOR | erythropoietin receptor |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FECH | ferrochelatase |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H4C | histone cluster 1, H4c |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| IREB2 | iron-responsive element binding protein 2 |
| IRGQ | immunity-related GTPase family, Q |
| ISCA1 | iron-sulfur cluster assembly 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA1109 | KIAA1109 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MANEA | mannosidase, endo-alpha |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MED20 | mediator complex subunit 20 |
| METAP2 | methionyl aminopeptidase 2 |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| MTM1 | myotubularin 1 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NIPBL | Nipped-B homolog (Drosophila) |
| NOTCH2 | notch 2 |
| NRP1 | neuropilin 1 |
| NTAN1 | N-terminal asparagine amidase |
| ORC3 | origin recognition complex, subunit 3 |
| ORC4 | origin recognition complex, subunit 4 |
| OSBPL3 | oxysterol binding protein-like 3 |
| PCBP2 | poly(rC) binding protein 2 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase |
| PCNX | pecanex homolog (Drosophila) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PEX1 | peroxisomal biogenesis factor 1 |
| PLK4 | polo-like kinase 4 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PTMA | prothymosin, alpha |
| RBM48 | RNA binding motif protein 48 |
| RBM8A | RNA binding motif protein 8A |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RCAN1 | regulator of calcineurin 1 |
| REV1 | REV1, polymerase (DNA directed) |
| RIOK3 | RIO kinase 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL10 | ribosomal protein L10 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SEC62 | SEC62 homolog (S. cerevisiae) |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SMC5 | structural maintenance of chromosomes 5 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPPL2B | signal peptide peptidase like 2B |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TANK | TRAF family member-associated NFKB activator |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM156 | transmembrane protein 156 |
| TOR1AIP1 | torsin A interacting protein 1 |
| TOX4 | TOX high mobility group box family member 4 |
| TPT1 | tumor protein, translationally-controlled 1 |
| TRIM14 | tripartite motif containing 14 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBB3 | tubulin, beta 3 class III |
| VASP | vasodilator-stimulated phosphoprotein |
| WASF1 | WAS protein family, member 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZNF280D | zinc finger protein 280D |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ACP2 | acid phosphatase 2, lysosomal |
| AKTIP | AKT interacting protein |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOD | apolipoprotein D |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BANP | BTG3 associated nuclear protein |
| BBC3 | BCL2 binding component 3 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD1A | CD1a molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CDK6 | cyclin-dependent kinase 6 |
| CEP131 | centrosomal protein 131kDa |
| CETN1 | centrin, EF-hand protein, 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN11 | claudin 11 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CRYM | crystallin, mu |
| CTAGE9 | CTAGE family, member 9 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTRL | chymotrypsin-like |
| DDA1 | DET1 and DDB1 associated 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DOK3 | docking protein 3 |
| DOLPP1 | dolichyldiphosphatase 1 |
| ENG | endoglin |
| ENO3 | enolase 3 (beta, muscle) |
| ERCC8 | excision repair cross-complementation group 8 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP2 | FK506 binding protein 2, 13kDa |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRPR | gastrin-releasing peptide receptor |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INO80D | INO80 complex subunit D |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JMJD4 | jumonji domain containing 4 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LXN | latexin |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MON1B | MON1 secretory trafficking family member B |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NPPA | natriuretic peptide A |
| NUBP2 | nucleotide binding protein 2 |
| OCEL1 | occludin/ELL domain containing 1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PMM1 | phosphomannomutase 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PSKH1 | protein serine kinase H1 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| QPRT | quinolinate phosphoribosyltransferase |
| RECQL4 | RecQ protein-like 4 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIRT6 | sirtuin 6 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SRPK3 | SRSF protein kinase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| STBD1 | starch binding domain 1 |
| STK25 | serine/threonine kinase 25 |
| THAP7 | THAP domain containing 7 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 |
| TMEM184B | transmembrane protein 184B |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| UBXN6 | UBX domain protein 6 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF189 | zinc finger protein 189 |
| ZNF510 | zinc finger protein 510 |
| ZNF85 | zinc finger protein 85 |
