| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the mafenide-2124 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATXN7L1 | ataxin 7-like 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| B9D1 | B9 protein domain 1 |
| BCAN | brevican |
| BFSP1 | beaded filament structural protein 1, filensin |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC88A | coiled-coil domain containing 88A |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP162 | centrosomal protein 162kDa |
| CEP72 | centrosomal protein 72kDa |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| DAPK3 | death-associated protein kinase 3 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ESRRA | estrogen-related receptor alpha |
| ETV4 | ets variant 4 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GOLGA2 | golgin A2 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HOOK1 | hook microtubule-tethering protein 1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IL6ST | interleukin 6 signal transducer |
| KIAA0485 | uncharacterized LOC57235 |
| KIF1C | kinesin family member 1C |
| KIF5C | kinesin family member 5C |
| LIG3 | ligase III, DNA, ATP-dependent |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NPTXR | neuronal pentraxin receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALMD | palmdelphin |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHF3 | PHD finger protein 3 |
| PIDD1 | p53-induced death domain protein 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PRR14L | proline rich 14-like |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBL2 | retinoblastoma-like 2 |
| REST | RE1-silencing transcription factor |
| RHOT2 | ras homolog family member T2 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SETD2 | SET domain containing 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIN1 | spindlin 1 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM231 | transmembrane protein 231 |
| TRIM62 | tripartite motif containing 62 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| UNKL | unkempt family zinc finger-like |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VGLL1 | vestigial-like family member 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF140 | zinc finger protein 140 |
| ZNF385D | zinc finger protein 385D |
| ZNF44 | zinc finger protein 44 |
| ZNF668 | zinc finger protein 668 |
| ZNF76 | zinc finger protein 76 |
| ZNF783 | zinc finger family member 783 |
| ZNF787 | zinc finger protein 787 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ABHD17B | abhydrolase domain containing 17B |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AFAP1 | actin filament associated protein 1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AMT | aminomethyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARRB2 | arrestin, beta 2 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAG4 | BCL2-associated athanogene 4 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC85C | coiled-coil domain containing 85C |
| CDON | cell adhesion associated, oncogene regulated |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CORO2A | coronin, actin binding protein, 2A |
| DBR1 | debranching RNA lariats 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EFNA3 | ephrin-A3 |
| EHD3 | EH-domain containing 3 |
| EHF | ets homologous factor |
| EN1 | engrailed homeobox 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLMN | glomulin, FKBP associated protein |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GOLGA8B | golgin A8 family, member B |
| GPATCH2L | G patch domain containing 2-like |
| GPR1 | G protein-coupled receptor 1 |
| GPR176 | G protein-coupled receptor 176 |
| GPR39 | G protein-coupled receptor 39 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST3H2A | histone cluster 3, H2a |
| HOXC5 | homeobox C5 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ICK | intestinal cell (MAK-like) kinase |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0753 | KIAA0753 |
| KIAA0754 | KIAA0754 |
| KIAA0894 | KIAA0894 protein |
| LINS | lines homolog (Drosophila) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGEH1 | melanoma antigen family H1 |
| MBTD1 | mbt domain containing 1 |
| MITF | microphthalmia-associated transcription factor |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MXD3 | MAX dimerization protein 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNB3 | plexin B3 |
| PRAME | preferentially expressed antigen in melanoma |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RIN1 | Ras and Rab interactor 1 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNX17 | sorting nexin 17 |
| TPCN1 | two pore segment channel 1 |
| TSPAN8 | tetraspanin 8 |
| TSPYL2 | TSPY-like 2 |
| VGLL3 | vestigial-like family member 3 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF408 | zinc finger protein 408 |
| ZNF606 | zinc finger protein 606 |
| ZNF671 | zinc finger protein 671 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |