mafenide-2287 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mafenide-2287 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACE2 angiotensin I converting enzyme 2
ACPP acid phosphatase, prostate
ACRV1 acrosomal vesicle protein 1
ADAM20 ADAM metallopeptidase domain 20
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
ALPPL2 alkaline phosphatase, placental-like 2
AQP3 aquaporin 3 (Gill blood group)
ARHGAP35 Rho GTPase activating protein 35
ARPIN actin-related protein 2/3 complex inhibitor
ATG10 autophagy related 10
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAIAP3 BAI1-associated protein 3
BIN1 bridging integrator 1
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C19ORF57 chromosome 19 open reading frame 57
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDRT1 CMT1A duplicated region transcript 1
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLSPN claspin
CPED1 cadherin-like and PC-esterase domain containing 1
CUL7 cullin 7
CXORF21 chromosome X open reading frame 21
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCN decorin
DSC3 desmocollin 3
DTX2 deltex 2, E3 ubiquitin ligase
DUX1 double homeobox 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECE1 endothelin converting enzyme 1
FAIM2 Fas apoptotic inhibitory molecule 2
FLRT2 fibronectin leucine rich transmembrane protein 2
GLIPR1 GLI pathogenesis-related 1
GSTTP1 glutathione S-transferase theta pseudogene 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HBB hemoglobin, beta
HEMK1 HemK methyltransferase family member 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIPK2 homeodomain interacting protein kinase 2
HIST1H1D histone cluster 1, H1d
HLF hepatic leukemia factor
IL11 interleukin 11
IL6ST interleukin 6 signal transducer
IQGAP1 IQ motif containing GTPase activating protein 1
LGALS8 lectin, galactoside-binding, soluble, 8
LRRC17 leucine rich repeat containing 17
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAOA monoamine oxidase A
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MED18 mediator complex subunit 18
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
N4BP1 NEDD4 binding protein 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
NNAT neuronatin
NPC1 Niemann-Pick disease, type C1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDCD3 NudC domain containing 3
OSBPL10 oxysterol binding protein-like 10
PACS1 phosphofurin acidic cluster sorting protein 1
PCDH12 protocadherin 12
PCM1 pericentriolar material 1
PER2 period circadian clock 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODNL1 podocan-like 1
POFUT1 protein O-fucosyltransferase 1
RAB6A RAB6A, member RAS oncogene family
RFPL3 ret finger protein-like 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
SFRP4 secreted frizzled-related protein 4
SKIL SKI-like proto-oncogene
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SSX3 synovial sarcoma, X breakpoint 3
STX2 syntaxin 2
SYNJ2 synaptojanin 2
TBCD tubulin folding cofactor D
TBX3 T-box 3
TBXA2R thromboxane A2 receptor
TEX15 testis expressed 15
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP53I11 tumor protein p53 inducible protein 11
TRIM38 tripartite motif containing 38
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF589 zinc finger protein 589
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
AHSP alpha hemoglobin stabilizing protein
ALPK1 alpha-kinase 1
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
BMP15 bone morphogenetic protein 15
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CD34 CD34 molecule
CD80 CD80 molecule
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN1 claudin 1
EFNA3 ephrin-A3
ERCC6 excision repair cross-complementation group 6
FAM212B family with sequence similarity 212, member B
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEM1C fem-1 homolog c (C. elegans)
FKBP10 FK506 binding protein 10, 65 kDa
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GEMIN8 gem (nuclear organelle) associated protein 8
GNG13 guanine nucleotide binding protein (G protein), gamma 13
H1F0 H1 histone family, member 0
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL28 kelch-like family member 28
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KREMEN2 kringle containing transmembrane protein 2
LAMB3 laminin, beta 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK10 mitogen-activated protein kinase 10
MYF5 myogenic factor 5
N4BP3 NEDD4 binding protein 3
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
NXPH4 neurexophilin 4
ODF2 outer dense fiber of sperm tails 2
PCDHB8 protocadherin beta 8
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
POMT2 protein-O-mannosyltransferase 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDM16 PR domain containing 16
PTPRU protein tyrosine phosphatase, receptor type, U
PYHIN1 pyrin and HIN domain family, member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFPL1S RFPL1 antisense RNA 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF121 ring finger protein 121
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SENP7 SUMO1/sentrin specific peptidase 7
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC17A2 solute carrier family 17, member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SPTBN2 spectrin, beta, non-erythrocytic 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THRAP3 thyroid hormone receptor associated protein 3
TIGD6 tigger transposable element derived 6
TPK1 thiamin pyrophosphokinase 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSPAN1 tetraspanin 1
USB1 U6 snRNA biogenesis 1
WDR33 WD repeat domain 33
WLS wntless Wnt ligand secretion mediator
XK X-linked Kx blood group
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZFHX3 zinc finger homeobox 3
ZFP37 ZFP37 zinc finger protein
ZNF205 zinc finger protein 205
ZNF532 zinc finger protein 532
ZNF76 zinc finger protein 76