mafenide-5079 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the mafenide-5079 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADGRL3 adhesion G protein-coupled receptor L3
AIM1L absent in melanoma 1-like
AIM2 absent in melanoma 2
ANGEL2 angel homolog 2 (Drosophila)
ANK1 ankyrin 1, erythrocytic
APAF1 apoptotic peptidase activating factor 1
ASIC1 acid sensing (proton gated) ion channel 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAIAP3 BAI1-associated protein 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BHMT2 betaine--homocysteine S-methyltransferase 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CALCRL calcitonin receptor-like
CASS4 Cas scaffolding protein family member 4
CCDC28B coiled-coil domain containing 28B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFHR5 complement factor H-related 5
CIDEB cell death-inducing DFFA-like effector b
CLCA2 chloride channel accessory 2
CLEC1A C-type lectin domain family 1, member A
COL21A1 collagen, type XXI, alpha 1
CORO2B coronin, actin binding protein, 2B
CPZ carboxypeptidase Z
CREB5 cAMP responsive element binding protein 5
DCLK2 doublecortin-like kinase 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
FABP1 fatty acid binding protein 1, liver
FAM49B family with sequence similarity 49, member B
FBXO4 F-box protein 4
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GIPR gastric inhibitory polypeptide receptor
GLE1 GLE1 RNA export mediator
GPATCH4 G patch domain containing 4
GPR22 G protein-coupled receptor 22
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRM4 glutamate receptor, metabotropic 4
GSK3A glycogen synthase kinase 3 alpha
GSTA1 glutathione S-transferase alpha 1
HDAC11 histone deacetylase 11
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HOXB2 homeobox B2
ICOSLG inducible T-cell co-stimulator ligand
IGKV3-20 immunoglobulin kappa variable 3-20
KCTD14 potassium channel tetramerization domain containing 14
KLHL22 kelch-like family member 22
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LINC00115 long intergenic non-protein coding RNA 115
LINC00260 long intergenic non-protein coding RNA 260
LOC729164 hCG1732469
LRRC1 leucine rich repeat containing 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP2K7 mitogen-activated protein kinase kinase 7
MC3R melanocortin 3 receptor
MDM4 MDM4, p53 regulator
MEF2D myocyte enhancer factor 2D
MFAP3L microfibrillar-associated protein 3-like
MMP13 matrix metallopeptidase 13
MMP9 matrix metallopeptidase 9
MTCP1 mature T-cell proliferation 1
MUC8 mucin 8
NPVF neuropeptide VF precursor
OLFM1 olfactomedin 1
PBX2 pre-B-cell leukemia homeobox 2
PHF7 PHD finger protein 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R7 protein phosphatase 1, regulatory subunit 7
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS50 protease, serine, 50
PTPRR protein tyrosine phosphatase, receptor type, R
RNF126P1 ring finger protein 126 pseudogene 1
RPS2 ribosomal protein S2
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SCAF4 SR-related CTD-associated factor 4
SCAPER S-phase cyclin A-associated protein in the ER
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEZ6L seizure related 6 homolog (mouse)-like
SOGA1 suppressor of glucose, autophagy associated 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULF1 sulfatase 1
TBCD tubulin folding cofactor D
TBXA2R thromboxane A2 receptor
TEX12 testis expressed 12
TNK2 tyrosine kinase, non-receptor, 2
TRIM33 tripartite motif containing 33
TTC12 tetratricopeptide repeat domain 12
USP2 ubiquitin specific peptidase 2
VCAN versican
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF460 zinc finger protein 460
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ATP13A2 ATPase type 13A2
BAK1 BCL2-antagonist/killer 1
BCAS3 breast carcinoma amplified sequence 3
BCL9 B-cell CLL/lymphoma 9
C14ORF93 chromosome 14 open reading frame 93
C4ORF29 chromosome 4 open reading frame 29
CA5B carbonic anhydrase VB, mitochondrial
CCDC176 coiled-coil domain containing 176
CD82 CD82 molecule
CFAP69 cilia and flagella associated protein 69
CIR1 corepressor interacting with RBPJ, 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNN1 calponin 1, basic, smooth muscle
CNPY3 canopy FGF signaling regulator 3
COG7 component of oligomeric golgi complex 7
CORT cortistatin
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRYL1 crystallin, lambda 1
CSF1R colony stimulating factor 1 receptor
CTNNBIP1 catenin, beta interacting protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF4 DDB1 and CUL4 associated factor 4
DLK2 delta-like 2 homolog (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EDIL3 EGF-like repeats and discoidin I-like domains 3
ETAA1 Ewing tumor-associated antigen 1
FDXR ferredoxin reductase
FPGS folylpolyglutamate synthase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GPX2 glutathione peroxidase 2
HIST1H3A histone cluster 1, H3a
HMHA1 histocompatibility (minor) HA-1
HOOK1 hook microtubule-tethering protein 1
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
ISYNA1 inositol-3-phosphate synthase 1
ITK IL2-inducible T-cell kinase
KIAA0355 KIAA0355
KLK6 kallikrein-related peptidase 6
LATS1 large tumor suppressor kinase 1
LTBP2 latent transforming growth factor beta binding protein 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MON1B MON1 secretory trafficking family member B
MPI mannose phosphate isomerase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRX1 NLR family member X1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PCOLCE procollagen C-endopeptidase enhancer
PHEX phosphate regulating endopeptidase homolog, X-linked
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRICKLE3 prickle homolog 3 (Drosophila)
PRR15L proline rich 15-like
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
QSER1 glutamine and serine rich 1
RNF31 ring finger protein 31
SCIN scinderin
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SH2D2A SH2 domain containing 2A
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRAL2 SIR2 antiphage like 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SOBP sine oculis binding protein homolog (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
STBD1 starch binding domain 1
STXBP2 syntaxin binding protein 2
SUGCT succinyl-CoA:glutarate-CoA transferase
SYTL2 synaptotagmin-like 2
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM159 transmembrane protein 159
TOR4A torsin family 4, member A
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
ZNF230 zinc finger protein 230
ZNF426 zinc finger protein 426
ZNF668 zinc finger protein 668
ZNF711 zinc finger protein 711
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787