make Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

200 genes co-occuring with the biological term make in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ADAM12 ADAM metallopeptidase domain 12
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADPGK ADP-dependent glucokinase
AFP alpha-fetoprotein
AGTR2 angiotensin II receptor, type 2
ALK anaplastic lymphoma receptor tyrosine kinase
AMH anti-Mullerian hormone
ANO1 anoctamin 1, calcium activated chloride channel
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BST1 bone marrow stromal cell antigen 1
CBFB core-binding factor, beta subunit
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK2 checkpoint kinase 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
COL1A1 collagen, type I, alpha 1
COL4A4 collagen, type IV, alpha 4
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CSTA cystatin A (stefin A)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCK deoxycytidine kinase
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DMD dystrophin
DND1 DND microRNA-mediated repression inhibitor 1
DPP4 dipeptidyl-peptidase 4
DRD4 dopamine receptor D4
EGF epidermal growth factor
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
ELN elastin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F11 coagulation factor XI
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
FOXP3 forkhead box P3
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GBA glucosidase, beta, acid
GBA2 glucosidase, beta (bile acid) 2
GCG glucagon
GEN1 GEN1 Holliday junction 5' flap endonuclease
GHRHR growth hormone releasing hormone receptor
GJB2 gap junction protein, beta 2, 26kDa
GPR1 G protein-coupled receptor 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IFNG interferon, gamma
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITLN1 intelectin 1 (galactofuranose binding)
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNIP2 Kv channel interacting protein 2
KDR kinase insert domain receptor
KLF1 Kruppel-like factor 1 (erythroid)
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS3 lectin, galactoside-binding, soluble, 3
LGI1 leucine-rich, glioma inactivated 1
LGMN legumain
LMO2 LIM domain only 2 (rhombotin-like 1)
LMO4 LIM domain only 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYZ lysozyme
MACROD2 MACRO domain containing 2
MADD MAP-kinase activating death domain
MAGEA4 melanoma antigen family A4
MAOA monoamine oxidase A
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAPT microtubule-associated protein tau
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIR126 microRNA 126
MIR203A microRNA 203a
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MOB4 MOB family member 4, phocein
MPG N-methylpurine-DNA glycosylase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSLN mesothelin
MSX1 msh homeobox 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH11 myosin, heavy chain 11, smooth muscle
NPSR1 neuropeptide S receptor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
OPA1 optic atrophy 1 (autosomal dominant)
PCNA proliferating cell nuclear antigen
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLN phospholamban
POLB polymerase (DNA directed), beta
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRKCG protein kinase C, gamma
PRKD2 protein kinase D2
PSEN1 presenilin 1
PSEN2 presenilin 2
PTCH1 patched 1
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBBP5 retinoblastoma binding protein 5
RN7SK RNA, 7SK small nuclear
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
S100A16 S100 calcium binding protein A16
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SELL selectin L
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPHS1 selenophosphate synthetase 1
SEPT2 septin 2
SEPT6 septin 6
SEPT7 septin 7
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC45A3 solute carrier family 45, member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLX4 SLX4 structure-specific endonuclease subunit
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX18 sorting nexin 18
SPI1 Spi-1 proto-oncogene
SPP1 secreted phosphoprotein 1
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STXBP1 syntaxin binding protein 1
TBX1 T-box 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
THBS1 thrombospondin 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP1 TIMP metallopeptidase inhibitor 1
TLN1 talin 1
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TRG T cell receptor gamma locus
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TWIST1 twist family bHLH transcription factor 1
VCL vinculin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VRK1 vaccinia related kinase 1
VWF von Willebrand factor
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZNF202 zinc finger protein 202